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ecdysone biosynthetic process

Known as: ecdysone anabolism, ecdysone biosynthesis, ecdysone formation 
The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis
Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In… Expand
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2013
2013
Silencing the ecdysone synthesis and signaling pathway genes disrupts nymphal development in the whitefly.
Sap-sucking insects are important pests in agriculture and good models to study insect biology. The role of ecdysone pathway… Expand
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Highly Cited
2012
Highly Cited
2012
Genome-wide patterns of latitudinal differentiation among populations of Drosophila melanogaster from North America
Understanding the genetic underpinnings of adaptive change is a fundamental but largely unresolved problem in evolutionary… Expand
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Review
2008
Review
2008
New players in the regulation of ecdysone biosynthesis.
Insect ecdysone steroid hormone regulates major developmental transitions, such as molting and metamorphosis. The production of… Expand
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2007
2007
Two independent duplications forming the Cyp307a genes in Drosophila.
The conserved relationship between orthologs of many cytochrome P450 genes involved in ecdysone synthesis is not reflected in the… Expand
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Highly Cited
2006
Highly Cited
2006
Neverland is an evolutionally conserved Rieske-domain protein that is essential for ecdysone synthesis and insect growth.
Steroid hormones mediate a wide variety of developmental and physiological events in multicellular organisms. During larval and… Expand
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2006
2006
Identification, characterization and developmental expression of Halloween genes encoding P450 enzymes mediating ecdysone biosynthesis in the tobacco hornworm, Manduca sexta.
The insect molting hormone 20-hydroxyecdysone (20E) plays a central role in regulating gene expression during development and… Expand
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Highly Cited
2005
Highly Cited
2005
Cytochrome P450 CYP307A1/Spook: a regulator for ecdysone synthesis in insects.
The prothoracic gland (PG) has essential roles in synthesizing and secreting a steroid hormone called ecdysone that is critical… Expand
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Highly Cited
2004
Highly Cited
2004
Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis.
We have reported recently the identification and characterization of the last three mitochondrial cytochrome P450 enzymes (CYP… Expand
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2004
2004
Cytogenetic and molecular aspects of position effect variegation in Drosophila melanogaster
A new genetic model system for studying position effect variegation in Drosophila melanogaster was found. It allows the analysis… Expand
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