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Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum.
The 70% MeOH extract of Ganoderma lucidum had an inhibitory effect on angiotensin converting enzyme activity, and from this extract, five new triterpenes, named ganoderal A, ganoderols A and B, andExpand
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Structure-activity relationship of brassinosteroids
Abstract The plant growth-promoting activities of brassinolide and brassinosteroids with different side chains were investigated by means of the Raphanus an
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Structure-activity relationship of brassinosteroids with respect to the A/B-ring functional groups
In order to examine the biological role of the A/B-ring functional groups of plant-growth-promoting brassinosteroids, twenty-three brassinosteroids with some modifications at rings A and B (1-15 andExpand
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Substrate specificity of adrenocortical cytochrome P-450scc--I. Effect of structural modification of cholesterol side-chain on pregnenolone production.
Abstract Thirty four cholesterol analogues with modified side chain were chemically synthesized and incubated with a highly purified preparation of cytochrome P-450scc. It was shown that five to tenExpand
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Bone resorbing activities of 24-hydroxy stereoisomers of 24-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3.
R and S isomers of 24-OH-D3 and 24,25-(OH)2D3 were tested for their effects on bone resorption in vitro. 24(R), 25-(OH)2D3 was more active than 24(S),25-(OH)2D3. Likewise, 24(R)-OH-D3 was more activeExpand
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Sitosterol-stimulative production of plasminogen activator in cultured endothelial cells from bovine carotid artery.
The endothelial cell is a rich source of plasminogen activator that is associated with fibrinolytic activity in blood vessel. Addition of sitosterol to the culture medium of endothelial cells fromExpand
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24- and 26-homo-1,25-dihydroxyvitamin D3: preferential activity in inducing differentiation of human leukemia cells HL-60 in vitro.
1,25-Dihydroxyvitamin D3, the hormonal form of vitamin D3, promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes. Differentiation changes include the induction ofExpand
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Conformational analysis of 1α,25-dihydroxyvitamin D3 by nuclear magnetic resonance
Abstract The conformational equilibrium of 1α,25-dihydroxyvitamin D3 (3) was studied by variable temperature 1H and 13C NMR spectroscopy. At temperatures below −100°C, two conformations in a ratio ofExpand
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