A. De Loof

Publications187
h-index44
Citations6,831
Highly Influential Citations263
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Characterization of the short neuropeptide F receptor from Drosophila melanogaster.
A seven transmembrane G-protein coupled receptor has been cloned from Drosophila melanogaster. This receptor shows structural similarities to vertebrate Neuropeptide Y(2) receptors and is activated… Expand
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Identification of the gregarization-associated dark-pigmentotropin in locusts through an albino mutant.
In response to crowding, locusts develop characteristic black patterns that are well discernible in the gregarious phase at outbreaks. We report here a dark-color-inducing neuropeptide… Expand
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Characterization of a Cloned Locust Tyramine Receptor cDNA by Functional Expression in Permanently Transformed Drosophila S2 Cells
Abstract: The cDNA for Tyr‐Loc, a G protein‐coupled receptor that clearly shows homology to a number of mammalian and fruit fly receptors for biogenic amines, was cloned from the nervous system of… Expand
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Peptidomic analysis of the larval Drosophila melanogaster central nervous system by two-dimensional capillary liquid chromatography quadrupole time-of-flight mass spectrometry.
Peptides are the largest class of signalling molecules found in animals. Nevertheless, in most proteomic studies peptides are overlooked since they literally fall through the mazes of the net. In… Expand
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Neuropeptidomic analysis of the brain and thoracic ganglion from the Jonah crab, Cancer borealis.
Mass spectrometric methods were applied to determine the peptidome of the brain and thoracic ganglion of the Jonah crab (Cancer borealis). Fractions obtained by high performance liquid chromatography… Expand
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Discovering neuropeptides in Caenorhabditis elegans by two dimensional liquid chromatography and mass spectrometry.
Completion of the Caenorhabditis elegans genome sequencing project in 1998 has provided more insight into the complexity of nematode neuropeptide signaling. Several C. elegans neuropeptide precursor… Expand
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SIFamide is a highly conserved neuropeptide: a comparative study in different insect species.
Neb-LFamide or AYRKPPFNGSLFamide was originally purified from the grey flesh fly Neobellieria bullata as a myotropic neuropeptide. We studied the occurrence of this peptide and its isoforms in the… Expand
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A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph.
Insects respond to microbial infection by the rapid and transient expression of several genes encoding antibacterial peptides. In this paper we describe a powerful technique, two-dimensional… Expand
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The myotropic peptides of Locusta migratoria: structures, distribution, functions and receptors.
The search for myotropic peptide molecules in the brain, corpora cardiaca, corpora allata suboesophageal ganglion complex of Locusta migratoria using a heterologous bioassay (the isolated hindgut of… Expand
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Peptidomics of the Larval Drosophila melanogasterCentral Nervous System*
Neuropeptides regulate most, if not all, biological processes in the animal kingdom, but only seven have been isolated and sequenced from Drosophila melanogaster. In analogy with the proteomics… Expand
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