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dexoxadrol

Known as: d-2,2-Diphenyl-4-(2-piperidyl)-1,3-dioxolane 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

AnalgesicsDioxolanesPiperidines

Narrower (1)

dexoxadrol hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1992
1992
Analogues of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure-activity relationships.
A series of dioxolane analogues based on dexoxadrol ((4S,6S)-2,2-diphenyl-4-(2-piperidyl)-1,3-dioxolane) and etoxadrol ((2S,4S,6S… 
Highly Cited
1990
Highly Cited
1990
Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (pcp) binding site: tentative evidence for pcp recognition sites not coupled to n-methyl-d…
1990
1990
Facilitation of GABA-induced depression with PCP and sigma receptor agonists was mediated through catecholaminergic pathways.
1988
1988
Psychotomimetic sigma‐ligands, dexoxadrol and phencyclidine block the same presynaptic potassium channel in rat brain.
1. Efflux of 86Rb from synaptosomes prepared from rat forebrain was used to assess voltage‐gated changes in K+ permeability in… 
Highly Cited
1987
Highly Cited
1987
Quantitative autoradiography of brain binding sites for the vesicular acetylcholine transport blocker 2-(4-phenylpiperidino)cyclohexanol (AH5183).
2-(4-Phenylpiperidino)cyclohexanol (AH5183) is a noncompetitive and potent inhibitor of high-affinity acetylcholine transport… 
Highly Cited
1986
Highly Cited
1986
Stereotyped behavior correlates better than ataxia with phencyclidine-receptor interactions.
1986
1986
Enhancement of brain calcium antagonist binding by phencyclidine and related compounds
Highly Cited
1985
Highly Cited
1985
Anticonvulsant properties of phencyclidine-like drugs in mice.
1985
1985
Regional heterogeneity of rat brain phencyclidine (PCP) receptors revealed by photoaffinity labeling with [3H] azido phencyclidine.
1984
1984
The effect of the dioxolanes on amino acid induced excitation in the mammalian spinal cord
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