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deslorelin

Known as: LHRH, Trp(6)-N-Et-GlyNH2(10)-, DSLN, LHRH, tryptophyl(6)-N-ethylglycinamide(10)- 
A synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (2)

Enzyme Inhibitorstriptorelin pamoate
Luteinizing Hormone-releasing Hormone AgonistNCIt Antineoplastic Agent Terminologyanalogs & derivativesdeslorelin 4.7 MG Drug Implant [Suprelorin]

Narrower (5)

OvuplantSomagardSucroMateSuprelorin

Papers overview

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Highly Cited
2004
Highly Cited
2004
Ovarian stimulation by concomitant administration of cetrorelix acetate and HMG following Diane-35 pre-treatment for patients with polycystic ovary syndrome: a prospective randomized study.
BACKGROUND Patients with polycystic ovary syndrome (PCOS) may need a longer period of pituitary downregulation to suppress the… 
Review
1992
Review
1992
Aromatization inhibition alone or in combination with GnRH agonists for the treatment of premenopausal breast cancer patients
Highly Cited
1990
Highly Cited
1990
FSH causes a time-dependent stimulation of preovulatory follicle growth in the absence of pulsatile LH secretion in ewes chronically treated with gonadotrophin-releasing hormone agonist.
The study investigated the relationship between the plasma concentration of FSH and the stimulation of preovulatory follicle… 
Highly Cited
1987
Highly Cited
1987
Clinical and hormonal effects of chronic gonadotropin-releasing hormone agonist treatment in polycystic ovarian disease.
Previously, we reported that short term administration of a highly potent GnRH agonist (GnRHa) for 1 month to patients with… 
Highly Cited
1987
Highly Cited
1987
Regulation of inhibin production by rat granulosa cells
Highly Cited
1986
Highly Cited
1986
Ovarian hyperstimulation for in-vitro fertilization controlled by GnRH agonist administered in combination with human menopausal gonadotrophins.
Surges of luteinizing hormone (LH) in serum that result in luteinization, but occur prematurely with respect to the diameter of… 
Highly Cited
1986
Highly Cited
1986
Characterization of a gonadotropin-releasing hormone receptor site in term placenta and chorionic villi.
The properties of GnRH receptor sites in the human placenta were analyzed by binding studies performed in particulate and… 
Highly Cited
1983
Highly Cited
1983
Fate of a gonadotropin-releasing hormone agonist internalized by rat pituitary gonadotrophs.
The intracellular fate of a radiolabeled GnRH agonist ([D-Ala6]des-Gly10-GnRH ethylamide) taken up by rat pituitary gonadotrophs… 
Highly Cited
1981
Highly Cited
1981
Desensitization to gonadotropin-releasing hormone observed in superfused pituitary cells on Cytodex beads.
Chronic exposure to gonadotropin-releasing hormone (GnRH) in vivo eventually results in a failure to maintain maximal… 
Highly Cited
1981
Highly Cited
1981
Hormonal regulation of cytodifferentiation and intercellular communication in cultured granulosa cells.
Granulosa cells from immature hypophysectomized diethylstilbestrol-treated rats displayed pronounced intracellular and… 
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