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Luteinizing Hormone-releasing Hormone Agonist

Known as: Gonadotropin releasing hormone analogues, endocrine therapy drugs, GnRH Agonist, Gonadotropin releasing hormone analogues 
A synthetic analogue of the endogenous hormone gonadotropin-releasing hormone (GnRH), with potential antineoplastic activity. Upon administration… 
National Institutes of Health

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NCIt Antineoplastic Agent Terminologydeslorelin

Papers overview

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2017
2017
GnRHa Treatment of Cryptorchid Boys Affects Genes Involved in Hormonal Control of the HPG Axis and Fertility
The gonadotropin-releasing hormone agonist (GnRHa; Buserelin) rescues fertility during adulthood in the majority of high… 
1986
1986
Heterogeneity of sperm density profiles following 16-week therapy with continuous infusion of high-dose LHRH analog plus testosterone.
LHRH agonist analogs have been investigated as potential male contraceptives. It has been shown that the LHRH agonistic analog [D… 
1984
1984
Regulation of prostaglandin E, progesterone, and cyclic adenosine monophosphate production in ovarian granulosa cells by luteinizing hormone and gonadotropin-releasing hormone agonist: comparative…
The early direct effects of GnRH on the ovary were investigated using cultured granulosa cells from preovulatory rat follicles… 
1983
1983
Testosterone supplementation attenuates the antifertility effects of an LHRH agonist in male rhesus monkeys.
Continuous administration of LHRH agonists in high doses disrupts pituitary and testicular function, thus providing an approach… 
1983
1983
Regulation of adenylate cyclase activity by follicle-stimulating hormone and a gonadotropin-releasing hormone agonist in cultured rat granulosa cells.
The effects of FSH and a GnRH agonist on adenylate cyclase activity and FSH receptor content were studied in granulosa cells… 
1983
1983
Effect of treatment for 1 year with a luteinizing hormone-releasing hormone agonist on ovarian, thyroidal, and adrenal function and menstruation in the stumptailed monkey (Macaca arctoides).
Nine adult stumptailed macaque monkeys with regular menstrual cycles were treated daily for 11–16 months with a LHRH agonist (5… 
1983
1983
Inhibitory actions of a gonadotropin-releasing hormone agonist on ovarian follicle-stimulating hormone receptors and adenylate cyclase in vivo.
The regulation of ovarian gonadotropin-sensitive adenylate cyclase and FSH receptors was studied in hypophysectomized… 
1982
1982
Study of the direct action of luteinizing hormone-releasing hormone agonists at the testicular level in intact rats treated with an antiluteinizing hormone serum.
Is it well known that LHRH agonists can inhibit testicular functions by gonadal desensitization secondary to endogenous LH… 
Highly Cited
1981
Highly Cited
1981
Hormonal regulation of cytodifferentiation and intercellular communication in cultured granulosa cells.
Granulosa cells from immature hypophysectomized diethylstilbestrol-treated rats displayed pronounced intracellular and… 
1981
1981
Binding characteristics of gonadotropin-releasing hormone receptors throughout the estrous cycle of the hamster.
The magnitude of LH secretion in response to exogenous gonadotropin-releasing hormone (GnRH) varies regularly through the stages…