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Luteinizing Hormone-releasing Hormone Agonist

Known as: Gonadotropin releasing hormone analogues, endocrine therapy drugs, GnRH Agonist, Gonadotropin releasing hormone analogues 
A synthetic analogue of the endogenous hormone gonadotropin-releasing hormone (GnRH), with potential antineoplastic activity. Upon administration… 
National Institutes of Health

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2 relations
NCIt Antineoplastic Agent Terminologydeslorelin

Papers overview

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Highly Cited
2011
Highly Cited
2011
Effect of luteinizing hormone-releasing hormone agonist on ovarian function after modern adjuvant breast cancer chemotherapy: the GBG 37 ZORO study.
PURPOSE Observational studies suggested that luteinizing hormone-releasing hormone agonists (LHRHa) might prevent premature… 
Review
2011
Review
2011
Association of androgen deprivation therapy with cardiovascular death in patients with prostate cancer: a meta-analysis of randomized trials.
CONTEXT Whether androgen deprivation therapy (ADT) causes excess cardiovascular deaths in men with prostate cancer is highly… 
Review
2006
Review
2006
The science behind 25 years of ovarian stimulation for in vitro fertilization.
To allow selection of embryos for transfer after in vitro fertilization, ovarian stimulation is usually carried out with… 
Highly Cited
2001
Highly Cited
2001
Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: a meta-analysis of four randomized trials.
PURPOSE The logic behind the application of luteinizing hormone-releasing hormone (LHRH) agonists in combination with tamoxifen… 
Highly Cited
2001
Highly Cited
2001
Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer.
BACKGROUND Treatment with a gonadotropin-releasing hormone agonist decreases bone mineral density and increases the risk of… 
Highly Cited
2000
Highly Cited
2000
Effects of gonadal steroids in women with a history of postpartum depression.
OBJECTIVE Endocrine factors are purported to play a role in the etiology of postpartum depression, but direct evidence for this… 
Highly Cited
2000
Highly Cited
2000
Ovarian stimulation with HMG: results of a prospective randomized phase III European study comparing the luteinizing hormone-releasing hormone (LHRH)-antagonist cetrorelix and the LHRH-agonist…
In this prospective and randomized study, 188 patients received the luteinizing hormone-releasing hormone (LHRH) antagonist… 
Highly Cited
1991
Highly Cited
1991
Induction of preovulatory luteinizing hormone surge and prevention of ovarian hyperstimulation syndrome by gonadotropin-releasing hormone agonist.
Highly Cited
1985
Highly Cited
1985
Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist
About one-third of human breast cancers require hormones for their continued growth1, and endocrine ablation or anti-hormone… 
Highly Cited
1980
Highly Cited
1980
Bioactive conformation of luteinizing hormone-releasing hormone: evidence from a conformationally constrained analog.
An analog of luteinizing hormone-releasing hormone containing a gamma-lactam as a conformational constraint has been prepared… 
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