• Publications
  • Influence
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins.
TLDR
The pH of the medial/trans-Golgi was measured and demonstrated that the Golgi membrane in intact cells is relatively permeable to H+, and that Cl- serves as a counter-ion for H+ transport and likely helps to maintain electroneutrality. Expand
JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA
TLDR
The tight junction is impervious to concentrated protein solutions and appears to function as a diffusion barrier or "seal," and the desmosome and probably also the zonula adhaerens may represent intercellular attachment devices. Expand
GOLPH3 Bridges Phosphatidylinositol-4- Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding
TLDR
The evidence suggests that GOLPH3 binds to PtdIns(4)P-rich trans-Golgi membranes and MYO18A conveying a tensile force required for efficient tubule and vesicle formation, which stretches the Golgi into the extended ribbon observed by fluorescence microscopy and the familiar flattened form observed by electron microscopy. Expand
The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage
THE DEVELOPMENT OF NEUTROPHILIC POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BONE MARROW
TLDR
The findings indicate that the situation is basically the same as described previously in the rabbit, insofar as the origin, enzymic activity, and persistence in the mature cell of the two types of granules are concerned. Expand
Podocalyxin activates RhoA and induces actin reorganization through NHERF1 and Ezrin in MDCK cells.
TLDR
It was found that full-length PC but not the PC mutant is connected to actin, induces redistribution of actin toward the apical membrane, and leads to increased RhoA activity. Expand
CELL JUNCTIONS IN AMPHIBIAN SKIN
TLDR
Interpreted in the light of current physiological data, these findings suggest that the diffusion of water, ions, and small, water-soluble molecules is impeded along the intercellular spaces of the epidermis by zonulae occludentes while it is facilitated from cell to cell within the epidesis by z onulae and maculae OccludENTes. Expand
Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion
TLDR
It is demonstrated that removal of heparan sulfate (but not other GAG) leads to a dramatic increase in the permeability of the GBM to NF. Expand
The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium
TLDR
The distribution of ZO-1 and the close developmental relationship between the two junctions suggest that the slit diaphragm is a variant of the tight junction that shares with it at least one structural protein and the functional property of defining distinctive plasmalemmal domains. Expand
GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP.
TLDR
Data provide direct evidence that the C terminus of a R GS protein is involved in interactions specific for a given RGS protein and implicates GAIP in regulation of additional functions besides its GAP activity. Expand
...
1
2
3
4
5
...