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desloratadine

Known as: 8-chloro-6,11-dihydro-11-(4-Piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine, desloratadine [Chemical/Ingredient], 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 
A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (3)

Cholinergic AntagonistsHistamine H1 Antagonists, Non-SedatingLoratadine

Narrower (2)

ClarinexSCH 34117
Desloratadine:MCnc:Pt:Bld:QnDesloratadine:MCnc:Pt:Ser/Plas:QnDesloratadine:MCnc:Pt:Urine:QnDrug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Structural characterization of in vitro rat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium…
In vitro drug metabolism study is an integral part of drug discovery process. In this report, we have described the application… 
Review
2008
Review
2008
Current advances in the management of urticaria
Urticaria is a relatively common autoimmune/autoreactive skin disorder that may severely impair quality of life. Although rarely… 
2007
2007
Determination of loratadine and its active metabolite in human plasma by high-performance liquid chromatography with mass spectrometry detection.
Highly Cited
2007
Highly Cited
2007
Response normalized liquid chromatography nanospray ionization mass spectrometry
Highly Cited
2006
Highly Cited
2006
Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy
ABSTRACT Objective: To assess the efficacy and onset of action of azelastine nasal spray and desloratadine tablets in patients… 
2006
2006
Effect of desloratadine on epithelial cell granulocyte‐macrophage colony‐stimulating factor secretion and eosinophil survival
Background Second‐generation antihistamines are H1 receptor antagonists and may have additional anti‐inflammatory effects. 
2005
2005
Increased nasal airflow with budesonide compared with desloratadine during the allergy season.
OBJECTIVE To compare the effects of desloratadine, an H1-blocking antihistamine, and budesonide, an intranasal corticosteroid, on… 
Review
2004
Review
2004
Current concepts and therapeutic strategies forallergic rhinitis in school-age children
2003
2003
Studies on performance and sleepiness with the H1-antihistamine, desloratadine.
INTRODUCTION The purpose of this study was to establish whether the H1-antihistamine desloratadine (5 mg), the active metabolite… 
2001
2001
Applications of new liquid chromatography-tandem mass spectrometry technologies for drug development support.
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