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desloratadine

Known as: 8-chloro-6,11-dihydro-11-(4-Piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine, desloratadine [Chemical/Ingredient], 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 
A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (3)

Cholinergic AntagonistsHistamine H1 Antagonists, Non-SedatingLoratadine

Narrower (2)

ClarinexSCH 34117
Desloratadine:MCnc:Pt:Bld:QnDesloratadine:MCnc:Pt:Ser/Plas:QnDesloratadine:MCnc:Pt:Urine:QnDrug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Structural characterization of in vitro rat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium…
In vitro drug metabolism study is an integral part of drug discovery process. In this report, we have described the application… 
Review
2009
Review
2009
Chronic urticaria: do urticaria nonexperts implement treatment guidelines? A survey of adherence to published guidelines by nonexperts
Background  Guidelines including level of evidence and grade of recommendation were recently published for chronic urticaria (CU… 
2009
2009
Safety and efficacy of desloratadine in chronic idiopathic urticaria in clinical practice: an observational study of 9246 patients
Background  Post‐marketing surveillance studies (PMSS) of medications are often mandated by authorities, provide crucial insights… 
Highly Cited
2007
Highly Cited
2007
Response normalized liquid chromatography nanospray ionization mass spectrometry
2007
2007
Selective inhibition of Kir currents by antihistamines.
2005
2005
Increased nasal airflow with budesonide compared with desloratadine during the allergy season.
OBJECTIVE To compare the effects of desloratadine, an H1-blocking antihistamine, and budesonide, an intranasal corticosteroid, on… 
Review
2005
Review
2005
Histamine-mediated mechanisms in the human nasal airway.
Review
2004
Review
2004
Current concepts and therapeutic strategies forallergic rhinitis in school-age children
2003
2003
Studies on performance and sleepiness with the H1-antihistamine, desloratadine.
INTRODUCTION The purpose of this study was to establish whether the H1-antihistamine desloratadine (5 mg), the active metabolite… 
2001
2001
Applications of new liquid chromatography-tandem mass spectrometry technologies for drug development support.
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