Histamine H1 Antagonists, Non-Sedating

Known as: antihistamine non sedating, antihistamines second generation, H1 Antihistamines, Non-Sedating 
A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine… (More)
National Institutes of Health

Related topics

Related topics

18 relations
Anti-Allergic AgentsIn Bloodaspects of radiation effectschemical synthesis
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Broader (1)

Antihistamines

Narrower (12)

AstemizoleCetirizineLoratadineOlopatadine hydrochloride
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Papers overview

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Review
2009
Review
2009
Allergic rhinitis and school performance.
Allergic rhinitis is presently the most common chronic disorder in the pediatric population. It can affect sleep at night and… (More)
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2007
2007
Levocetirizine does not prolong the QT/QTc interval in healthy subjects: results from a thorough QT study
To conduct a thorough QT study of levocetirizine, a non-sedating antihistamine, in accordance with International Conference on… (More)
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Review
2006
Review
2006
Functional gastrointestinal disorders and mast cells: implications for therapy.
The pathophysiology of functional gastrointestinal disorders is poorly understood. Accepted common mechanisms include… (More)
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Review
2006
Review
2006
Effect of H1 antihistamines upon the central nervous system.
The antihistamines have been divided into fi rst and second generation drugs, according to their pharmacokinetic properties… (More)
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2005
2005
Levocetirizine in children: evidenced efficacy and safety in a 6-week randomized seasonal allergic rhinitis trial.
Studies evaluating newer antihistamines in children are few. Levocetirizine is a potent and highly selective H1-antihistamine… (More)
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Review
2004
Review
2004
Chronic urticaria: aetiology, management and current and future treatment options.
Chronic urticaria is a common condition that can be very disabling when severe. A cause for chronic idiopathic urticaria (CIU) is… (More)
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2003
2003
P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine.
Recent in vitro studies have suggested that P-glycoprotein (Pgp) and passive membrane permeability may influence the brain… (More)
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1999
1999
Cardiovascular safety of fexofenadine HCl.
BACKGROUND Certain first- and second-generation H1-receptor antagonists are associated with prolongation of the corrected QT… (More)
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Highly Cited
1998
Highly Cited
1998
Diagnosis and management of rhinitis: complete guidelines of the Joint Task Force on Practice Parameters in Allergy, Asthma and Immunology. American Academy of Allergy, Asthma, and Immunology.
This document contains complete guidelines for diagnosis and management of rhinitis developed by the Joint Task Force on Practice… (More)
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1997
1997
Electrocardiographic findings in patients with diphenhydramine overdose.
QT interval prolongation and torsades de pointes ventricular tachycardia have been reported after therapeutic doses and… (More)
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