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dalfampridine

Known as: 4-Aminopyridine, FAMPRIDINE (4-AMINOPYRIDINE), 4-Pyridinamine 
One of the POTASSIUM CHANNEL BLOCKERS, with secondary effect on calcium currents, which is used mainly as a research tool and to characterize channel… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
A previous phase 3 study showed significant improvement in walking ability in multiple sclerosis (MS) patients treated with oral… 
Highly Cited
1999
Highly Cited
1999
BACKGROUND The Brugada syndrome is characterized by marked ST-segment elevation in the right precordial ECG leads and is… 
Highly Cited
1996
Highly Cited
1996
BACKGROUND The J wave is a deflection that appears in the ECG as a late delta wave following the QRS or as a small secondary R… 
Highly Cited
1994
Highly Cited
1994
We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv) channels (Kv1.1, Kv1.2, Kv1.3, Kv1.5, and… 
Highly Cited
1991
Highly Cited
1991
MITOCHONDRIA take up and extrude various inorganic and organic ions, as well as larger substances such as proteins1–4. The… 
Highly Cited
1989
Highly Cited
1989
In vitro intracellular recordings were made from neurons in the rat midbrain slice. Two neuronal types could be distinguished in… 
Review
1987
Review
1987
  • J. Storm
  • Journal of Physiology
  • 1987
  • Corpus ID: 45747009
1. The repolarization of the action potential, and a fast after‐hyperpolarization (a.h.p.) were studied in CA1 pyramidal cells (n… 
Highly Cited
1984
Highly Cited
1984
The ionic requirements for electro‐responsiveness in thalamic neurones were studied using in vitro slice preparations of the… 
Highly Cited
1984
Highly Cited
1984
Membrane receptors and ion transport mechanisms probably have an important role in lymphocyte activation leading to T-lymphocyte… 
Highly Cited
1979
Highly Cited
1979
We describe the design and operation of a machine that freezes biological tissues by contact with a cold metal block, which…