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dalfampridine

Known as: 4-Aminopyridine, FAMPRIDINE (4-AMINOPYRIDINE), 4-Pyridinamine 
One of the POTASSIUM CHANNEL BLOCKERS, with secondary effect on calcium currents, which is used mainly as a research tool and to characterize channel… 
National Institutes of Health

Related topics

Related topics

25 relations
12 HR dalfampridine 10 MG Extended Release Oral Tablet [Ampyra]FAMPRIDINE (4-AMINOPYRIDINE) PWDRIn Bloodagonists

Narrower (15)

2,4-diaminopyridine2-amino-5-bromopyridine3,4-diaminopyridine3-methoxy-4-aminopyridine

Broader (1)

Potassium Channel Blockers

Papers overview

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Highly Cited
1999
Highly Cited
1999
Dopamine modulates two potassium currents and inhibits the intrinsic firing properties of an identified motor neuron in a central pattern generator network.
The two pyloric dilator (PD) neurons are components [along with the anterior burster (AB) neuron] of the pacemaker group of the… 
Highly Cited
1996
Highly Cited
1996
Characterization of an ultrarapid delayed rectifier potassium channel involved in canine atrial repolarization.
1. Depolarizing pulses positive to 0 mV elicit a transient outward current (Ito) and a sustained ‘pedestal’ current in canine… 
Highly Cited
1990
Highly Cited
1990
Membrane currents in visually identified motoneurones of neonatal rat spinal cord.
1. Ionic currents induced by depolarization of motoneurones were analysed by tight‐seal, whole‐cell recording in thin slices of… 
Highly Cited
1989
Highly Cited
1989
The role of potassium channels in Schwann cell proliferation in Wallerian degeneration of explant rabbit sciatic nerves.
1. Patch clamp studies of whole‐cell ionic currents and biochemical studies of proliferation were carried out on Schwann cells of… 
Highly Cited
1988
Highly Cited
1988
Transient calcium‐dependent potassium current in magnocellular neurosecretory cells of the rat supraoptic nucleus.
1. Magnocellular neurosecretory neurones were impaled in the supraoptic nucleus of perfused explants of rat hypothalamus… 
Highly Cited
1986
Highly Cited
1986
Calcium activated potassium channels in cultured astrocytes
Highly Cited
1984
Highly Cited
1984
Calcium-mediated inactivation of the calcium conductance in cesium- loaded frog heart cells
Ca current inactivation was investigated in frog atrial muscle under voltage-clamp conditions. To inhibit the outward currents… 
Highly Cited
1983
Highly Cited
1983
Effects of extracellular potassium concentration on the excitability of the parallel fibres of the rat cerebellum.
1. Field potentials and extracellular potassium concentration, [K+]o, were recorded from the rat cerebellar cortex using ion… 
Highly Cited
1980
Highly Cited
1980
Inhibitory action of adenosine on synaptic transmission in the hippocampus of the guinea pig in vitro.
Highly Cited
1979
Highly Cited
1979
Calcium‐dependent potentials in the mammalian sympathetic neurone.
1. Intracellular recordings from post‐ganglionic neurones of the rat superior cervical ganglion revealed two non‐synaptic… 
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