dalfampridine

Known as: 4-Aminopyridine, FAMPRIDINE (4-AMINOPYRIDINE), 4-Pyridinamine 
One of the POTASSIUM CHANNEL BLOCKERS, with secondary effect on calcium currents, which is used mainly as a research tool and to characterize channel… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
OBJECTIVE A previous phase 3 study showed significant improvement in walking ability in multiple sclerosis (MS) patients treated… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The Brugada syndrome is characterized by marked ST-segment elevation in the right precordial ECG leads and is… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND The J wave is a deflection that appears in the ECG as a late delta wave following the QRS or as a small secondary R… (More)
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Highly Cited
1996
Highly Cited
1996
A long-standing question in neurobiology is whether astrocytes respond to the neuronal release of neurotransmitters in vivo. To… (More)
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Highly Cited
1994
Highly Cited
1994
We have analyzed the biophysical and pharmacological properties of five cloned K+ (Kv) channels (Kv1.1, Kv1.2, Kv1.3, Kv1.5, and… (More)
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Highly Cited
1991
Highly Cited
1991
MITOCHONDRIA take up and extrude various inorganic and organic ions, as well as larger substances such as proteins1–4. The… (More)
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Highly Cited
1989
Highly Cited
1989
In vitro intracellular recordings were made from neurons in the rat midbrain slice. Two neuronal types could be distinguished in… (More)
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Review
1987
Review
1987
1. The repolarization of the action potential, and a fast after-hyperpolarization (a.h.p.) were studied in CA1 pyramidal cells (n… (More)
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Highly Cited
1984
Highly Cited
1984
The ionic requirements for electro-responsiveness in thalamic neurones were studied using in vitro slice preparations of the… (More)
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Highly Cited
1979
Highly Cited
1979
We describe the design and operation of a machine that freezes biological tissues by contact with a cold metal block, which… (More)
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