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Potassium Channel Blockers
Known as:
Blockers, Potassium Channel
, Channel Blockers, Potassium
, potassium channel blocker
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION…
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National Institutes of Health
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Related topics
Related topics
41 relations
Narrower (32)
3,4-diaminopyridine
5,8-diethoxypsoralen
Aek toxin
Amiodarone
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Anti-Arrhythmia Agents
In Blood
KATP Channels
Vasodilator Agents
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Pulmonary vasoconstrictor action of KCNQ potassium channel blockers
Shreena Joshi
,
P. Balan
,
A. Gurney
Respiratory Research
2006
Corpus ID: 15635261
BackgroundKCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important…
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Highly Cited
2006
Highly Cited
2006
Randomized, double-blind, placebo-controlled crossover pilot study of a potassium channel blocker in patients with septic shock*
S. Warrillow
,
M. Egi
,
R. Bellomo
Critical Care Medicine
2006
Corpus ID: 21898399
Background:Marked potassium efflux prevents calcium entry into vascular smooth muscle cells and may be responsible for the…
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Review
2005
Review
2005
A systematic review of currently available pharmacological neuroprotective agents as a sole intervention before anticipated or induced cardiac arrest.
M. Weigl
,
G. Tenze
,
+5 authors
M. Dworschak
Resuscitation
2005
Corpus ID: 25638374
Highly Cited
2004
Highly Cited
2004
Treatment of episodic ataxia type 2 with the potassium channel blocker 4-aminopyridine
M. Strupp
,
R. Kalla
,
M. Dichgans
,
T. Freilinger
,
S. Glasauer
,
T. Brandt
Neurology
2004
Corpus ID: 40296038
Patients with episodic ataxia type 2 (EA2) can often be successfully treated with acetazolamide. The authors report three…
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Highly Cited
2004
Highly Cited
2004
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation
R. Dost
,
A. Rostock
,
C. Rundfeldt
Naunyn-Schmiedeberg's Archives of Pharmacology
2004
Corpus ID: 21282530
Retigabine (N-(2-amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester) has a broad anticonvulsant spectrum and is…
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Highly Cited
1995
Highly Cited
1995
Mechanism of block of a human cardiac potassium channel by terfenadine racemate and enantiomers
T. Yang
,
C. Prakash
,
D. Roden
,
D. Snyders
British Journal of Pharmacology
1995
Corpus ID: 25303726
1 The cardiac toxicity of racemic terfenadine (marked QT prolongation and polymorphic ventricular arrhythmias) is probably due to…
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Highly Cited
1995
Highly Cited
1995
Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans.
P. Smits
,
S. Williams
,
D. Lipson
,
P. Banitt
,
G. Rongen
,
M. Creager
Circulation
1995
Corpus ID: 33929198
BACKGROUND The endogenous nucleoside adenosine plays an important role in the regulation of vascular tone, especially during…
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Highly Cited
1992
Highly Cited
1992
Canine left ventricular hypertrophy predisposes to ventricular tachycardia induction by phase 2 early afterdepolarizations after administration of BAY K 8644.
J. Ben-David
,
D. Zipes
,
G. Ayers
,
H. P. Pride
Journal of the American College of Cardiology
1992
Corpus ID: 85122
Highly Cited
1989
Highly Cited
1989
Anti-ischemic effects of the potassium channel activators pinacidil and cromakalim and the reversal of these effects with the potassium channel blocker glyburide.
G. Grover
,
J. Mccullough
,
D. Henry
,
M. Conder
,
P. Sleph
Journal of Pharmacology and Experimental…
1989
Corpus ID: 40557398
The direct cardioprotective efficacy of the potassium channel activators pinacidil and cromakalim was determined in isolated…
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Highly Cited
1985
Highly Cited
1985
Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart.
M. Mestre
,
T. Carriot
,
+6 authors
G. Le Fur
Life Science
1985
Corpus ID: 22670319
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