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Potassium Channel Blockers

Known as: Blockers, Potassium Channel, Channel Blockers, Potassium, potassium channel blocker 
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Background:Marked potassium efflux prevents calcium entry into vascular smooth muscle cells and may be responsible for the… Expand
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Highly Cited
2006
Highly Cited
2006
BackgroundKCNQ channels have been widely studied in the nervous system, heart and inner ear, where they have important… Expand
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Highly Cited
2004
Highly Cited
2004
Patients with episodic ataxia type 2 (EA2) can often be successfully treated with acetazolamide. The authors report three… Expand
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Highly Cited
2004
Highly Cited
2004
Retigabine (N-(2-amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester) has a broad anticonvulsant spectrum and is… Expand
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1996
1996
OBJECTIVES Monophosphoryl lipid A (MLA), a detoxified derivative of the lipid A portion of the endotoxin molecule, given as a… Expand
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Highly Cited
1995
Highly Cited
1995
1 The cardiac toxicity of racemic terfenadine (marked QT prolongation and polymorphic ventricular arrhythmias) is probably due to… Expand
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Highly Cited
1995
Highly Cited
1995
BACKGROUND The endogenous nucleoside adenosine plays an important role in the regulation of vascular tone, especially during… Expand
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Highly Cited
1989
Highly Cited
1989
The direct cardioprotective efficacy of the potassium channel activators pinacidil and cromakalim was determined in isolated… Expand
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Highly Cited
1985
Highly Cited
1985
PK 11195, an antagonist of the peripheral type benzodiazepine receptor, does not affect either the duration of the action… Expand
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Highly Cited
1978
Highly Cited
1978
3,4-diaminopyridine has been found to act very potently in selectively blocking the potassium channels of squid axon membranes… Expand
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