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Amiodarone

Known as: Amiodarone [Chemical/Ingredient], Amiodarona, 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone 
An iodine-rich benzofuran derivative with antiarrhythmic and vasodilatory activities. As a class III antiarrhythmic agent, amiodarone blocks the… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (15)

ATI 2001AmiodaronaCordaroneHO-3538
Amiodarone hydrochlorideAmiodarone:MCnc:Pt:Ser/Plas:QnAmiodarone:SCnc:Pt:Ser/Plas:QnAtrial Repolarization [PE]

Broader (8)

Anti-Arrhythmia AgentsBenzofuransCytochrome P-450 CYP2C9 InhibitorsCytochrome P-450 CYP2D6 Inhibitors

Papers overview

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Highly Cited
1993
Highly Cited
1993
A preliminary C-band scatterometer model function for the ERS-1 AMI instrument
Highly Cited
1992
Highly Cited
1992
Dextromethorphan and Mephenytoin Phenotyping of Patients Treated with Thioridazine or Amitriptyline
The metabolism of most tricyclic antidepressants and some phenothiazine neuroleptics is under the genetic control of hepatic… 
Highly Cited
1989
Highly Cited
1989
The complete sequence of soybean chlorotic mottle virus DNA and the identification of a novel promoter.
The complete nucleotide sequence of an infectious clone of soybean chlorotic mottle virus (SoyCMV) DNA was determined and… 
Highly Cited
1987
Highly Cited
1987
Comparative electrophysiologic effects of intravenous amiodarone and desethylamiodarone in dogs: evidence for clinically relevant activity of the metabolite.
It has been suggested that some of the effects of long-term amiodarone therapy may be due to accumulation of a metabolite… 
Highly Cited
1986
Highly Cited
1986
Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.
The mechanisms of the resistance of intestinal cancer to anthracyclines were studied on an experimental model of rat colon cancer… 
1984
1984
Delayed ventricular depolarization--correlation with ventricular activation and relevance to ventricular fibrillation in acute myocardial infarction.
Signal averaging to detect abnormalities in the terminal phase of ventricular depolarization has been performed in several groups… 
Highly Cited
1980
Highly Cited
1980
Suppression of normal granulopoiesis in vitro by a leukemia-associated inhibitor (LAI) of acute and chronic leukemia.
To determine if normal granulopoiesis can be suppressed by substances produced by cells from patients with leukemia. conditioned… 
Highly Cited
1979
Highly Cited
1979
Amiodarone in the treatment of refractory supraventricular and ventricular arrhythmias
Amiodarone is an antiarrhythmic agent unrelated to other drugs in current use. It has been little used in Britain, and no formal… 
1975
1975
Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
A greater persistence of unbound (exchangeable) drug in tumor cells versus drug-limiting normal tissue (proliferating epithelium… 
Highly Cited
1953
Highly Cited
1953
Estimation of the antileukemic potency of the antimetabolite aminopterin, administered alone and in combination with citrovorum factor or folic acid.
Summary A comparison has been made, with reference to drug dose mortality response, of the relative effectiveness of the…