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Sudden cardiac arrest associated with early repolarization.
BACKGROUND Early repolarization is a common electrocardiographic finding that is generally considered to be benign. Its potential to cause cardiac arrhythmias has been hypothesized from experimentalExpand
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Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans.
Brugada syndrome is a genetic disease associated with sudden cardiac death that is characterized by ventricular fibrillation and right precordial ST segment elevation on ECG. Loss-of-functionExpand
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Impending epidemic: future projection of heart failure in Japan to the year 2055.
BACKGROUND The future burden of heart failure in Japan was projected to 2055 in order to prospectively estimate of the number of these patients. METHODS AND RESULTS The statistics are based onExpand
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Prevalence of atrial fibrillation in the general population of Japan: an analysis based on periodic health examination.
BACKGROUND The mortality and morbidity rates of various cardiovascular diseases differ between Western countries and Japan. The age- and gender-specific prevalence rate of atrial fibrillation (AF) inExpand
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Metabolic Syndrome and Risk of Development of Atrial Fibrillation: The Niigata Preventive Medicine Study
Background— The metabolic syndrome consists of a cluster of atherosclerotic risk factors, many of which also have been implicated in the genesis of atrial fibrillation (AF). However, the precise roleExpand
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Characteristics of recurrent ventricular fibrillation associated with inferolateral early repolarization role of drug therapy.
OBJECTIVES Our purpose was to evaluate the efficacy of antiarrhythmic drugs (AADs) in recurrent ventricular fibrillation (VF) associated with inferolateral early repolarization pattern on theExpand
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Long-Term Prognosis of Probands With Brugada-Pattern ST-Elevation in Leads V1–V3
Background—The prognosis of patients with saddleback or noncoved type (non–type 1) ST-elevation in Brugada syndrome is unknown. The purpose of this study was to clarify the long-term prognosis ofExpand
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Close bidirectional relationship between chronic kidney disease and atrial fibrillation: the Niigata preventive medicine study.
BACKGROUND Atrial fibrillation (AF) and chronic kidney disease share risk factors and pathophysiologic mechanisms, suggesting that two conditions have close relationships. METHODS This is aExpand
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Polymorphisms of tumor necrosis factor-alpha and interleukin-10 genes in Japanese patients with idiopathic dilated cardiomyopathy.
Various cytokines play important roles in the pathogenesis of congestive heart failure. TNF-alpha is one of the pro-inflammatory cytokines, and IL-10 has anti-inflammatory actions. The -308 (G / A)Expand
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Electrocardiographic Characteristics and SCN5A Mutations in Idiopathic Ventricular Fibrillation Associated With Early Repolarization
Background— Recently, we and others reported that early repolarization (J wave) is associated with idiopathic ventricular fibrillation. However, its clinical and genetic characteristics are unclear.Expand
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