Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 237,885,502 papers from all fields of science
Search
Sign In
Create Free Account
cyclin-dependent protein kinase activity
Known as:
cdk-activating kinase activity
, cyclin-dependent protein kinase, intrinsic catalyst activity
, cyclin-dependent protein serine/threonine kinase activity
Expand
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
15 relations
CDC2 Protein Kinase
CDK2 gene
CDK4 gene
CDK5 gene
Expand
Broader (1)
Cell Cycle Control
Narrower (1)
cyclin binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Radiomics risk score (RRS) on CT to predict survival and response to CDK 4/6 inhibitors in hormone receptor (HR) positive metastatic breast cancer (MBC).
S. Kunte
,
Nathaniel Braman
,
+4 authors
A. Madabhushi
2020
Corpus ID: 219780211
e13041Background: The addition of CDK 4/6 inhibitors (CDK) to endocrine therapy (ET) is the standard of care for HR+ MBC…
Expand
Review
2018
Review
2018
Abstract P3-14-02: Incidence of venous thromboembolism in patients with hormone receptor-positive HER2-negative metastatic breast cancer treated with CDK 4/6 inhibitors: A systematic review and meta…
K. Thein
,
M. Zaw
,
+4 authors
T. Oo
2018
Corpus ID: 79828728
Background: The cyclin dependent kinases (CDK) along with their partners, the cyclins, have a crucial role in regulation of the…
Expand
2017
2017
Abstract 5525: Induced expression of PPM1A in ER-negative breast cancer cells inhibits growth by suppressing CDK phosphorylation
A. Mazumdar
,
Jamal L Hill
,
+5 authors
P. Brown
2017
Corpus ID: 80031388
2016
2016
Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
Guo Zhang
,
Margaret A. Park
,
+10 authors
P. Dent
Journal of Biological Chemistry
2016
Corpus ID: 44666908
In Fig. 3A, the image of mouse hepatocytes overexpressing p21 and treated with PD184352 (PD) and deoxycholic acid (DCA) was…
Expand
2015
2015
Abstract P6-02-01: Identification of subgroups of triple negative breast cancer cells with selective responses to mTOR, CDK, mitotic and proteasome inhibitors
Prson Gautam
,
Leena Karhinen
,
+4 authors
K. Wennerberg
2015
Corpus ID: 70363526
Triple negative breast cancer (TNBC) is characterized by the lack of of estrogen, progesterone and HER2/ErbB2 receptors. It is a…
Expand
2013
2013
Abstract S4-04: Overcoming resistance to PI3K inhibitors in PIK3CA mutant breast cancer using CDK4/6 inhibition: Results from a combinatorial drug screen
S. Vora
,
Nayoon Kim
,
+10 authors
J. Engelman
2013
Corpus ID: 72221171
Various components of the phosphatidylinositol 3-kinase (PI3K) pathway are deregulated across a spectrum of human cancers…
Expand
2012
2012
Targeting CDK in triple-negative breast cancer
Kai Lou
2012
Corpus ID: 71646905
UCSF researchers have found that the majority of triple-negative breast cancers have a dysregulated MYC pathway and the group has…
Expand
2010
2010
Abstract 3490: Selective estrogen receptor modulators enhance efficacy of small molecule CDK inhibitors on human breast cancer cells differing in the expression of ER
J. Węsierska-Gądek
,
Nora Zulehner
,
Oxana Komina
,
Margarita Maurer
2010
Corpus ID: 56512002
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Inactivation of cyclin-dependent kinases (CDKs) by…
Expand
2009
2009
Resistant Primary Bone Marrow Myeloma Transcriptional Regulation in β TGF-CDK 2 Phosphorylation of Smad 2 Disrupts
S. Chen‐Kiang
,
H. Cho
,
+5 authors
R. Niesvizky
2009
Corpus ID: 207769314
2007
2007
Cell cycle control and plant development
D. Inzé
2007
Corpus ID: 82545005
1. The growing family of plant cyclin-dependent kinases with multiple functions in cellular and developmental regulation. 2. The…
Expand