CDC2 Protein Kinase

Known as: p34 (cdc2), p34CDC2, p34(CDC2) 
Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
In the early embryonic cell cycle, Cdc2–cyclin B functions like an autonomous oscillator, whose robust biochemical rhythm… (More)
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Highly Cited
2000
Highly Cited
2000
Protein kinases have proved to be largely resistant to the design of highly specific inhibitors, even with the aid of… (More)
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Highly Cited
1999
Highly Cited
1999
Recently Gadd45, a p53-regulated stress protein, has been implicated in the activation of a G2/M checkpoint after damage by UV… (More)
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Highly Cited
1998
Highly Cited
1998
Mitotic fragmentation of the Golgi apparatus can be largely explained by disruption of the interaction between GM130 and the… (More)
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Highly Cited
1997
Highly Cited
1997
The G2 DNA damage checkpoint ensures maintenance of cell viability by delaying progression into mitosis in cells which have… (More)
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Highly Cited
1995
Highly Cited
1995
Cdc2 is the cyclin-dependent kinase that controls entry of cells into mitosis. Phosphorylation of Cdc2 on threonine-14 and… (More)
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Highly Cited
1994
Highly Cited
1994
L86-8275 [(-) cis-5,7-dihydroxy-2-(2-chlorophenyl)-8[4-(3-hydroxy-1- methyl)-piperidinyl]-4H-benzopyran-4-one] directly inhibits… (More)
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Highly Cited
1992
Highly Cited
1992
Recent studies have shown that there exists a family of protein kinases structurally and functionally related to the yeast cell… (More)
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Highly Cited
1991
Highly Cited
1991
A new human cyclin, named cyclin E, was isolated by complementation of a triple cln deletion in S. cerevisiae. Cyclin E showed… (More)
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Highly Cited
1989
Highly Cited
1989
The cdc2+ protein kinase (pp34) is found to be phosphorylated on tyrosine as well as serine and threonine residues in… (More)
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