CDK5 gene

Known as: CDK5, Cyclin-Dependent Kinase 5 Gene, CYCLIN-DEPENDENT KINASE 5 
This gene is involved in neuronal regulation and is involved in the development of the mammalian central nervous system.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
CDK5 is an important kinase in nervous system function, controlling neural development and postsynaptic signal integration. Here… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Alzheimer's disease is a major cause of dementia for which treatments remain unsatisfactory. Cyclin-dependent kinase 5 (CDK5) is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Synaptic vesicle endocytosis (SVE) is triggered by calcineurin-mediated dephosphorylation of the dephosphin proteins. SVE is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2001
Review
2001
Since it was identified a decade ago, cyclin-dependent kinase 5 (CDK5) has emerged as a crucial regulator of neuronal migration… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Cocaine enhances dopamine-mediated neurotransmission by blocking dopamine re-uptake at axon terminals. Most dopamine-containing… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Recent studies suggest that increased activity of cyclin-dependent kinase 5 (Cdk5) may contribute to neuronal death and… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The physiological state of the cell is controlled by signal transduction mechanisms which regulate the balance between protein… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Cyclin-dependent kinase 5 (Cdk5) was originally isolated by its close homology to the human CDC2 gene, which is a key regulator… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The adult mammalian cortex is characterized by a distinct laminar structure generated through a well-defined pattern of neuronal… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Although cyclin-dependent kinase 5 (Cdk5) is closely related to other cyclin-dependent kinases, its kinase activity is detected… (More)
Is this relevant?