CDK2 gene

Known as: Cyclin Dependent Kinase 2 Gene, p33(CDK2), CYCLIN-DEPENDENT KINASE 2 
This gene is involved in G2/M cell cycle regulation.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Most RNAs generated by the human genome have no protein-coding ability and are termed non-coding RNAs. Among these include… (More)
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Highly Cited
2006
Highly Cited
2006
The function of cyclin-dependent kinase 2 (CDK2) is often abolished after DNA damage. The inhibition of CDK2 plays a central role… (More)
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Highly Cited
2004
Highly Cited
2004
The genomic organization of the CDK2 gene, which overlaps the melanocyte-specific gene SILV/PMEL17, poses an interesting… (More)
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Highly Cited
2003
Highly Cited
2003
We have investigated the contribution of CDK4 and CDK2 inhibition to G1 arrest in colon cancers following inhibition of the MEK… (More)
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Highly Cited
1997
Highly Cited
1997
CDK inhibitors are thought to prevent cell proliferation by negatively regulating cyclin-CDK complexes. We propose that the… (More)
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Highly Cited
1997
Highly Cited
1997
Growth of prostatic epithelial cells is androgen-dependent; however, the mechanism of androgen action on cell growth is not well… (More)
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Highly Cited
1995
Highly Cited
1995
In normal human fibroblasts, cyclin A-CDK2 exists in a quaternary complex that contains p21 and PCNA. In many transformed cells… (More)
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Highly Cited
1993
Highly Cited
1993
THE major events of the cell division cycle are triggered by periodic changes in the activity of cyclin-dependent protein kinases… (More)
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Highly Cited
1993
Highly Cited
1993
A two-hybrid protein interaction screen was used to isolate cDNAs encoding human proteins that can interact with human CDK2 in… (More)
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Highly Cited
1992
Highly Cited
1992
We have examined the role of phosphorylation in the regulation of human cyclin-dependent kinase-2 (CDK2), a protein closely… (More)
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