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CDK2 gene
Known as:
Cyclin Dependent Kinase 2 Gene
, p33(CDK2)
, CYCLIN-DEPENDENT KINASE 2
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This gene is involved in G2/M cell cycle regulation.
National Institutes of Health
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Related topics
Related topics
8 relations
CDK2 protein, human
Cell Cycle Control
DNA Replication
Phosphorylation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Design , Synthesis and Biological Evaluation of dihydropyrimidine derivatives as potential anticancer agents
Jamelah S. Al‐Otaibi
,
Tarek M. el Gogary
,
D. Ibrahim
2018
Corpus ID: 106405792
CDK2, which plays a vital role as a regulator of cell growth, is one of the intensely studied TK targets of anticancer inhibitors…
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2017
2017
Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine…
Gennady M Verkhivker
Molecular Biosystems
2017
Corpus ID: 32656818
The overarching goal of delineating molecular principles underlying differentiation of the activation mechanisms in cyclin…
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2016
2016
In silico methods reconfirm CDK2 as a potential molecular target of 5-fluorouracil
V. Yata
,
S. Mahajan
,
+4 authors
V. S. Mattaparthi
2016
Corpus ID: 56087200
Vinod Kumar Yata1, Shweta Mahajan1, Arun Thapa1, Shadab Ahmed2, Akash Deep Biswas3, Airy Sanjeev3&Venkata Satish Kumar…
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2013
2013
Let-7 c Inhibits NSCLC Cell Proliferation by Targeting HOXA 1
M. Zhan
,
Q. Qu
,
+5 authors
Hong-Hao Zhou
2013
Corpus ID: 28179905
MicroRNAs (miRNAs) represent a class of endogenous, single-strand and highly conserved noncoding small RNAs. They post…
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2012
2012
An association study of germline polymorphisms in CCNE1 and CDK2 with breast cancer risk, tumor characteristics and survival in a Chinese Han population
H. Wang
,
Fang Wg
,
+6 authors
S. Ap
2012
Corpus ID: 78549409
2010
2010
Cancer esearch ention and Epidemiology binatorial Chemoprevention Reveals a Novel oothened-Independent Role of GLI 1 in R phageal Carcinogenesis
ra Rizvi
,
C. Demars
,
+7 authors
N. Buttar
2010
Corpus ID: 29418200
Download ux-induced injury promotes esophageal adenocarcinoma, one of the most rapidly increasing, highly lencers in Western…
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2008
2008
Cisplatin-induced cytoxicity: is the nucleus relevant?
D. Sheikh-Hamad
AJP - Renal Physiology
2008
Corpus ID: 35521025
cisplatin is a potent chemotherapeutic agent widely used for the treatment of cancer. However, cisplatin is frequently associated…
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2007
2007
Human TopBP 1 Participates in Cyclin E / CDK 2 Activation and Preinitiation Complex Assembly during G 1 / S Transition *
Yesu Jeon
,
Kyung Yong Lee
,
M. Ko
,
Y. Lee
,
Sukhyun Kang
,
D. Hwang
2007
Corpus ID: 3160952
Human TopBP1 with eight BRCA1 C terminus domains has been mainly reported to be involved in DNA damage response pathways.Herewe…
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Review
2006
Review
2006
Different Mechanisms of CDK 5 and CDK 2 Activation as Revealed by CDK 5 / p 25 and CDK 2 / Cyclin A Dynamics
M. Otyepka
,
Iveta Bártová
,
Z. Kříž
,
J. Koča
2006
Corpus ID: 39437646
A detailed analysis is presented of the dynamics of human CDK5 in complexes with the protein activator p25 and the purine-like…
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2000
2000
The Rb-CDK 4 / 6 Signaling Pathway Is Critical in Neural Precursor Cell Cycle Regulation *
K. Ferguson
,
S. Callaghan
,
M. O'hare
,
David S. Park
,
R. Slack
2000
Corpus ID: 35472853
The tumor suppressor, retinoblastoma (Rb), is involved in both terminal mitosis and neuronal differentiation. We hypothesized…
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