CDK4 gene

Known as: CDK4, Cyclin-Dependent Kinase 4 Gene, CELL DIVISION KINASE 4 
This gene is involved in G1 stage cell cycle progression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
0204019932017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Deregulated miRNAs participate in colorectal carcinogenesis. In this study, miR-218 was found to be downregulated in human… (More)
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Highly Cited
2006
Highly Cited
2006
Sphingosine kinase (Sphk) enzymes are important in intracellular sphingolipid metabolism as well as in the biosynthesis of… (More)
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Highly Cited
2002
Highly Cited
2002
The Tax oncoprotein of human T-cell leukemia virus type 1 (HTLV-1) induces leukemia in transgenic mice and permanent T-cell… (More)
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Highly Cited
2001
Highly Cited
2001
We have introduced a point mutation in the first coding exon of the locus encoding the cyclin-dependent kinase 4 (Cdk4) by… (More)
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Highly Cited
2000
Highly Cited
2000
The prototypic oncogene c-MYC encodes a transcription factor that can drive proliferation by promoting cell-cycle reentry… (More)
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Highly Cited
2000
Highly Cited
2000
Survivin is a recently described inhibitor of apoptosis. Because suppression of apoptosis is important for carcinogenesis and… (More)
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Highly Cited
1997
Highly Cited
1997
The Rb/p16 tumor-suppressive pathway is abrogated frequently in human tumors, either through inactivation of the Rb or p16INK4a… (More)
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Highly Cited
1996
Highly Cited
1996
We applied an enzyme-linked immunospot (ELISPOT) assay for the detection and quantification of blood-derived CD8+ T cells… (More)
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Highly Cited
1994
Highly Cited
1994
A putative tumor suppressor locus on the short arm of human chromosome 9 has been localized to a region of less than 40 kilobases… (More)
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Highly Cited
1994
Highly Cited
1994
Recently, it has been shown that a gene encoding the cyclin-dependent kinase 4 inhibitory protein, p16, is frequently targeted… (More)
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