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connective tissue growth factor

Known as: IGFBP-8, IBP-8, Insulin-Like Growth Factor Binding Protein 8 
Connective tissue growth factor protein (349 aa, ~38kDa) is encoded by the human CTGF gene. This protein plays a role in the promotion of… 
National Institutes of Health

Related topics

Related topics

27 relations
CTGF geneCell Differentiation processCell Proliferation Regulatory ProcessConnective tissue growth factor:MCnc:Pt:Urine:Qn

Narrower (3)

CTGF protein, humanCtgf protein, mouseCtgf protein, rat

Broader (2)

Growth FactorImmediate-Early Proteins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Connective tissue growth factor is increased in pseudoexfoliation glaucoma.
PURPOSE Pseudoexfoliation (PXF) syndrome is a generalized disorder of the extracellular matrix (ECM) involving the trabecular… 
Highly Cited
2010
Highly Cited
2010
Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin.
Reduced production of type I procollagen is a prominent feature of chronologically aged human skin. Connective tissue growth… 
Highly Cited
2009
Highly Cited
2009
Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen.
OBJECTIVE Connective tissue growth factor (CTGF; CCN2) is overexpressed in systemic sclerosis (SSc) and has been hypothesized to… 
Highly Cited
2006
Highly Cited
2006
Pathogenic Role of Connective Tissue Growth Factor (CTGF/CCN2) in Osteolytic Metastasis of Breast Cancer
The role of CTGF/CCN2 in osteolytic metastasis by breast cancer cells and its mechanism of action were studied. Osteolytic… 
Highly Cited
2004
Highly Cited
2004
Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61)
Connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61) are prototypical members of the CCN family which also… 
Highly Cited
2004
Highly Cited
2004
Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex
Connective-tissue growth factor (CTGF) is a member of the CCN family of secreted proteins. CCN family members contain four… 
Highly Cited
2004
Highly Cited
2004
Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis.
Connective tissue growth factor (CTGF/CCN2) is one of the candidate factors mediating fibrogenic activity of TGF-beta. It was… 
Highly Cited
2004
Highly Cited
2004
CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin.
In vivo, CCN2 (connective tissue growth factor) promotes angiogenesis, osteogenesis, tissue repair, and fibrosis, through largely… 
Highly Cited
2003
Highly Cited
2003
Connective Tissue Growth Factor Is a Mediator of Angiotensin II–Induced Fibrosis
Background—Angiotensin II (Ang II) participates in the development of fibrosis during vascular damage. Connective tissue growth… 
Highly Cited
2001
Highly Cited
2001
Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF.
Connective tissue growth factor (CTGF) is a growth and chemotactic factor for fibroblasts encoded by an immediate early gene that… 
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