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cloricromen

Known as: cloricromene, 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarboxylmethoxycoumarin, Acetic acid, ((8-chloro-3-(2-(diethylamino)ethyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy)-, ethyl ester 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

AD-6 (8-chlorocarbochromen)

Broader (2)

ChromonarPlatelet Aggregation Inhibitors
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Preparation and characterization of eudragit retard nanosuspensions for the ocular delivery of cloricromene.
The purpose of this study was to improve the stability of cloricromene (AD6) in ophthalmic formulations and its drug availability… 
1997
1997
Cloricromene Reduces Myocardial Infarct Size in Rabbits When Administered During the Early Reperfusion Period
Cloricromene is a coumarin derivative without anticoagulant activities that has recently been found to decrease myocardial… 
1995
1995
Tumor necrosis factor induces E-selectin production in splanchnic artery occlusion shock.
Splanchnic arteries were clamped for 45 min to induce splanchnic artery occlusion (SAO) shock in anesthetized rats. Sham-operated… 
1995
1995
Multiple actions of the coumarine derivative cloricromene and its protective effects on ischemic brain injury
The effects of different doses (0.25, 0.5, 1 and 2 mg/kg/i.p.) of cloricromene, a coumarine derivative, have been investigated on… 
1994
1994
Beneficial effects of cloricromene in ischemic reperfused myocardium.
Cloricromene (Clo) has been used to prevent myocardial damage after transient occlusion of the circumflex coronary artery (Cx… 
1993
1993
Cloricromene inhibits G-protein-mediated activation of phospholipase A2 in human platelets.
The coumarin derivative, cloricromene, an antithrombotic drug previously indicated as AD6, is known to inhibit the release of… 
1991
1991
Polymorphonuclear leukocyte-dependent modulation of platelet function: effect of cloricromene.
1990
1990
Cloricromene inhibits the activation of human platelets by ADP alone or in combination with adrenaline.
1987
1987
The increase of the openings of the surface-connected canalicular system in weakly stimulated platelets is prevented by a carbochromen derivative. A computerized morphometric analysis of freeze…
1986
1986
Ultrastructural modifications of the platelet plasma membrane in vascular diseases and the effect of a carbochromen derivative as studied by freeze-fracture and computer measurement.
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