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Comparison of Lipid Peroxidation and Myocardial Damage Induced by Adriamycin and 4′-Epiadriamycin in Mice
Adriamycin (ADM) and 4′-epiadriamycin (4′-ADM) were given to mice in a single dose of 15 mg/kg body weight (i.p.). Twenty-five mice were alloted to 3 groups. One group (Group I; n = 8) was given ADM;Expand
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Adriamycin-induced myocardial toxicity: new solutions for an old problem?
Adriamycin is a potent and broad-spectrum antineoplastic agent that plays a major role in cancer chemotherapy. Unfortunately, its use has been hampered by conventional toxicities and cardiotoxicityExpand
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Relationship between oxidative stress, lipid peroxidation, and ultrastructural damage in patients with coronary artery disease undergoing cardioplegic arrest/reperfusion.
OBJECTIVE In animal models, formation of oxidants during postischemic reperfusion may exert deleterious effects ("oxidative stress"). Cardioplegic arrest/reperfusion during cardiac surgery mightExpand
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Carotid Artery Stenting Protected With an Emboli Containment System
Background and Purpose— Fear of distal embolization and stroke has aroused concern regarding carotid stenting. Devices to protect the cerebral circulation may make carotid stenting safer. Methods— AExpand
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Chagas cardiomyopathy: Europe is not spared!
Chagas’ disease was first described in 1909 by the Brazilian physician Carlos Chagas, who named the parasite Trypanosoma cruzi after his mentor, Oswaldo Cruz.1 It causes more deaths in the AmericasExpand
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Autonomic Neuropathy and Painless Myocardial Infarction in Diabetic Patients: Histologic Evidence of Their Relationship
Myocardial infarction is considered the prime cause of death among adult diabetic patients. In a great number of cases, during myocardial infarction the patients don't feel pain or it is atypical.Expand
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Amelioration of adriamycin-induced cardiotoxicity in rabbits by prenylamine and vitamins A and E.
The cardioprotective potentials of prenylamine (a calcium antagonist) and of a combination of vitamins A and E (a singlet oxygen quencher and a free radical scavenger, respectively) were evaluated inExpand
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Protection of Distal Embolization in High-Risk Patients with Acute ST-Segment Elevation Myocardial Infarction (PREMIAR).
Distal embolization may decrease myocardial reperfusion after primary percutaneous coronary intervention (PCI). Nonetheless, results of previous trials assessing the role of distal protection duringExpand
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Prognostic impact of Chagas disease in the United States.
A prior publication from our group reported the fact that Chagas disease is underdiagnosed. This review will summarize several aspects of Chagas disease in the United States including modes ofExpand
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Nocturnal hypertension defined by fixed cut-off limits is a better predictor of left ventricular hypertrophy than non-dipping.
The classification of subjects as nocturnal hypertensives in accordance with non-dipping (i.e. systolic blood pressure - BP - fall <10%) is less reproducible as compared to the fixed cut-off limitsExpand
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