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cevimeline

Known as: Cevimelina, 2-methyspiro(1,3-oxathiolane-5,3)quinuclidine, cevimeline [Chemical/Ingredient] 
A cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds to and activates muscarinic receptors, thereby increasing the… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (5)

AF-102BCevimeline hydrochlorideEvoxacFKS 508
Angle Closure GlaucomaAsthmaIritis

Broader (4)

Muscarinic AgonistsParasympathomimetic AgentsQuinuclidinesThiophenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites.
2012
2012
Generation and functional analysis of monoclonal antibodies against the second extracellular loop of human M3 muscarinic acetylcholine receptor
The M3 muscarinic acetylcholine receptor (M3R) plays a crucial role in the activation of salivary and lachrymal glands. The M3R… 
2006
2006
Assessment of the use of sialogogues in the clinical management of patients with xerostomia.
This study was conducted to assess the clinical efficacy and adverse effects of pilocarpine, bethanechol and cevimeline in… 
Review
2005
Review
2005
Recent advances in the management of ocular complications of sjögren’s syndrome
Sjögren’s syndrome (SS) is an autoimmune disorder, the principal ocular manifestation of which is decreased tear production… 
2004
2004
Traitement actuel de la xérostomie au cours du syndrome de Sjögren
2003
2003
Effects of Pilocarpine Hydrochloride and Cevimeline on Submandibular/ Sublingual Salivation in Rat Xerostomia Model Produced by X-Ray Irradiation
Summary The present study was performed to assess the effects of pilocarpine hydrochloride ((3S,4R)-3-ethyl-dihydro-4-[(1-methyl… 
2002
2002
AF150(S) and AF267B: M1 muscarinic agonists as innovative therapies for Alzheimer's disease.
The M1 muscarinic agonists AF102B (Cevimeline, EVOXACTM: prescribed in USA and Japan for Sjogren's Syndrome), AF150(S) and AF267B… 
Highly Cited
2002
Highly Cited
2002
AF150(S) and AF267B
The M1 muscarinic agonists AF102B (Cevimeline, EVOXACTM: prescribed in USA and Japan for Sjogren’s Syndrome), AF150(S) and AF267B… 
Review
2000
Review
2000
Approaches to the treatment of Sjögren's syndrome.
Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by complaints of sicca symptoms (dry eye and mouth) and… 
Review
2000
Review
2000
Sjögren’s syndrome: current therapies remain inadequate for a common disease
Sjögren’s syndrome (SS) is a systematic autoimmune disease characterised by dysfunction of the lacrimal and salivary glands. This… 
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