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cevimeline

Known as: Cevimelina, 2-methyspiro(1,3-oxathiolane-5,3)quinuclidine, cevimeline [Chemical/Ingredient] 
A cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds to and activates muscarinic receptors, thereby increasing the… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (5)

AF-102BCevimeline hydrochlorideEvoxacFKS 508
Angle Closure GlaucomaAsthmaIritis

Broader (4)

Muscarinic AgonistsParasympathomimetic AgentsQuinuclidinesThiophenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Mode of interaction of 1,4-dioxane agonists at the M2 and M3 muscarinic receptor orthosteric sites.
2012
2012
Generation and functional analysis of monoclonal antibodies against the second extracellular loop of human M3 muscarinic acetylcholine receptor
The M3 muscarinic acetylcholine receptor (M3R) plays a crucial role in the activation of salivary and lachrymal glands. The M3R… 
2011
2011
Management of xerostomia and salivary gland hypofunction.
Xerostomia and salivary gland hypofunction are conditions that have been associated with increased prevalence of caries… 
2010
2010
Dosage form design and in vitro/in vivo evaluation of cevimeline extended-release tablet formulations.
2009
2009
Cevimeline for the treatment of dry mouth in patients with Sjogren's syndrome
Sjogren's Syndrome (SS) is a chronic autoimmune disease characterized by the presence of xerostomia and xerophthalmia and by the… 
2009
2009
Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts.
Previous reports suggested that there is no significant difference in the binding affinity of pilocarpine and cevimeline on… 
2009
2009
Cevimeline enhances the excitability of rat superior salivatory neurons.
Cevimeline, a therapeutic drug for xerostomia, is an agonist of muscarinic acetylcholine receptors (mAChRs), and directly… 
Review
2005
Review
2005
Recent advances in the management of ocular complications of sjögren’s syndrome
Sjögren’s syndrome (SS) is an autoimmune disorder, the principal ocular manifestation of which is decreased tear production… 
2004
2004
Traitement actuel de la xérostomie au cours du syndrome de Sjögren
2003
2003
Xerostomía en el paciente anciano
La disminucion de la secrecion salival provoca la sequedad bucal o xerostomia que puede alterar la calidad de vida de las… 
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