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AF-102B

Known as: AF 102B, AF102B 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
M1 muscarinic receptors (M1 mAChRs) play a role in an apparent linkage of three major hallmarks of Alzheimer’s disease (AD… 
Highly Cited
2000
Highly Cited
2000
β‐Amyloid (Aβ) deposits in diffuse and compact senile plaques in the brain are one of the defining histopathological features of… 
Highly Cited
1998
Highly Cited
1998
Abstract: Full and functionally selective M1 muscarinic agonists (carbachol and AF102B, respectively) activate secretion of the… 
Highly Cited
1996
Highly Cited
1996
Abstract: Hyperphosphorylated τ proteins are the principal fibrous component of the neurofibrillary tangle pathology in Alzheimer… 
Review
1996
Review
1996
The AF series compounds, AF102B and congeners of AF150(S), are functionally selective agonists for m1 muscarinic receptors… 
Highly Cited
1994
Highly Cited
1991
Highly Cited
1991
AF102B [(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine], a structurally rigid analog of acetylcholine, was…