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Cevimeline hydrochloride

Known as: cevimeline hcl 
A cholinergic analogue with glandular secretion stimulatory activity. Cevimeline binds to and activates muscarinic receptors, thereby increasing the… 
National Institutes of Health

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AF-102BEvoxac
Cytochrome P450 2D6, humancevimelinecytochrome P450 3A4 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
[A study of the sialogogic effect of cevimeline gargle].
The purpose of this study was to clarify the sialogogic effect iveness of cevimeline gargle. Sequential comparison tests were… 
2010
2010
Impact of gastrointestinal residence time of extended-release (ER) tablets on in vivo evaluation of ER tablets
2009
2009
Effects of cevimeline on the immunolocalization of aquaporin-5 and the ultrastructure of salivary glands in Sjögren's syndrome model mice.
Sjögren's syndrome (SS) is an autoimmune disorder whose main symptoms include xerostomia and dry eyes. It has been demonstrated… 
2007
2007
Treatment of Human Dry Mouth Using Various Medicines
There is no effective therapy for dry mouth, although the number of patients with this condition has been increasing in recent… 
2005
2005
Prosthodontic management of patients with xerostomia
2005
2005
Cevimeline hydrochloride improved cholinergic dysfunction in a patient with pure autonomic failure
Sirs: Patients with multiple system atrophy (MSA), pure autonomic failure (PAF), or familial amyloid neuropathy (FAP) show… 
Review
2004
Review
2004
Transplantation of Cultured Salivary Gland Cells into an Atrophic Salivary Gland
Patients with dry mouth have been treated with salivary substitutes and/or medications such as pilocarpine or cevimeline… 
2004
2004
Phase III Study of Cevimeline for Radiation-Induced Xerostomia
2004
2004
Study on the use of cevimeline hydrochloride hydrate for psychosomatic oral disease
Many psychosomatic dental patients, including those with glossalgia, also suffer from oral xerosis. Gum-chewing tests typically… 
Review
2002
Review
2002
[Cevimeline hydrochloride hydrate (Saligren capsule 30 mg): a review of its pharmacological profiles and clinical potential in xerostomia].
  • A. Shiozawa
  • Nihon yakurigaku zasshi. Folia pharmacologica…
  • 2002
  • Corpus ID: 22954463
Cevimeline hydrochloride hydrate is a muscarinic receptor agonist with a chemical structure of a quinuclidine. Intraduodenal… 
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