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caspase

Known as: cystein protease, Caspases [Chemical/Ingredient], Peptidase Family C14 
Caspases are a family of intracellular cysteine proteinases involved in inflammation and apoptosis. These enzymes appear to be involved in the… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Inflammatory caspases (caspase-1, -4, -5 and -11) are critical for innate defences. Caspase-1 is activated by ligands of various… 
Review
2013
Review
2013
Caspases are a family of endoproteases that provide critical links in cell regulatory networks controlling inflammation and cell… 
Review
2004
Review
2004
Caspases, which are the executioners of apoptosis, comprise two distinct classes, the initiators and the effectors. Although… 
Review
1999
Review
1999
Caspases are crucial mediators of programmed cell death (apoptosis). Among them, caspase-3 is a frequently activated death… 
Review
1998
Review
1998
Apoptosis, an evolutionarily conserved form of cell suicide, requires specialized machinery. The central component of this… 
Highly Cited
1998
Highly Cited
1998
Caspases are intracellular proteases that function as initiators and effectors of apoptosis. The kinase Akt and p21-Ras, an Akt… 
Highly Cited
1998
Highly Cited
1998
The homeostasis of animals is regulated not only by the growth and differentiation of cells, but also by cell death through a… 
Highly Cited
1998
Highly Cited
1998
Interleukin 1β-converting enzyme-like proteases (caspases) are crucial components of cell death pathways. Among the caspases… 
Review
1997
Review
1997
Apoptosis is a major form of cell death, characterized initially by a series of stereotypic morphological changes. In the…