Calpain

Known as: Papain-Like Cysteine Protease, Neutral Proteinase, Calcium-Dependent, Proteinase, Calcium-Dependent Neutral 
Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Calpains are a family of proteases that were scientifically recognized earlier than proteasomes and caspases, but remain… (More)
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Review
2011
Review
2011
The calpains are a conserved family of cysteine proteinases that catalyse the controlled proteolysis of many specific substrates… (More)
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Highly Cited
2006
Highly Cited
2006
Autophagy-related gene (Atg) 5 is a gene product required for the formation of autophagosomes. Here, we report that Atg5, in… (More)
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Highly Cited
2004
Highly Cited
2004
Dynamic regulation of adhesion complexes is required for cell migration and has therefore emerged as a key issue in the study of… (More)
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Highly Cited
2004
Highly Cited
2004
The structural clues of substrate recognition by calpain are incompletely understood. In this study, 106 cleavage sites in… (More)
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Review
2003
Review
2003
The calpain system originally comprised three molecules: two Ca2+-dependent proteases, mu-calpain and m-calpain, and a third… (More)
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Highly Cited
2000
Highly Cited
2000
Cyclin-dependent kinase 5 (cdk5) and its neuron-specific activator p35 are required for neurite outgrowth and cortical lamination… (More)
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Highly Cited
2000
Highly Cited
2000
Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately… (More)
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Review
2000
Review
2000
Both necrotic and apoptotic neuronal death are observed in various neurological and neurodegenerative disorders. Calpain is… (More)
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Highly Cited
1988
Highly Cited
1988
One of the obstacles encountered when extracting DNA from a large number of samples is the cumbersome method of deprotein-izing… (More)
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