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Calpain

Known as: Papain-Like Cysteine Protease, Neutral Proteinase, Calcium-Dependent, Proteinase, Calcium-Dependent Neutral 
Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from… 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Autophagy-related gene (Atg) 5 is a gene product required for the formation of autophagosomes. Here, we report that Atg5, in… 
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Highly Cited
2004
Highly Cited
2004
Dynamic regulation of adhesion complexes is required for cell migration and has therefore emerged as a key issue in the study of… 
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Review
2003
Review
2003
The calpain system originally comprised three molecules: two Ca2+-dependent proteases, mu-calpain and m-calpain, and a third… 
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Highly Cited
2000
Highly Cited
2000
Cyclin-dependent kinase 5 (cdk5) and its neuron-specific activator p35 are required for neurite outgrowth and cortical lamination… 
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Highly Cited
2000
Highly Cited
2000
Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately… 
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Review
2000
Review
2000
Both necrotic and apoptotic neuronal death are observed in various neurological and neurodegenerative disorders. Calpain is… 
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Highly Cited
1995
Highly Cited
1995
Limb-girdle muscular dystrophies (LGMDs) are a group of inherited diseases whose genetic etiology has yet to be elucidated. The… 
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Review
1994
Review
1994
Calpain, calcium‐activated neutral protease, stands as a unique receptor for calcium signals in biological systems; its… 
Highly Cited
1991
Highly Cited
1991
In genetic linkage studies using the restriction fragment length polymorphism (RFLP) technique, it is essential to process… 
Highly Cited
1988
Highly Cited
1988
One of the obstacles encountered when extracting DNA from a large number of samples is the cumbersome method of deprotein-izing…