Skip to search formSkip to main contentSkip to account menu

caspase-6

Known as: MCH2, Apoptotic Protease Mch-2, Caspase 6 
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 7; CASPASE 8; and CASPASE… 
National Institutes of Health

Related topics

Related topics

33 relations
ApoptosisCASP2 protein, humanCASP4 protein, humanCASP6 gene

Broader (1)

Cysteine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Bonding in cationic MCH2+ (M=K-La, Hf-Rn): a theoretical study on periodic trends.
DFT and CCSD(T) calculations have been performed to investigate the bonding situation of 54 cationic methylene complexes, MCH(2… 
Highly Cited
2008
Highly Cited
2008
Arsenic trioxide decreases AKT protein in a caspase-dependent manner
Arsenic trioxide (As2O3) is used clinically to treat acute promyelocytic leukemia but is less successful in other malignancies… 
Highly Cited
2007
Highly Cited
2007
Cell death after co-administration of cisplatin and ethacrynic acid
Highly Cited
2006
Highly Cited
2006
Evidence that caspase‐1 is a negative regulator of AMPA receptor‐mediated long‐term potentiation at hippocampal synapses
Best known for their pivotal role in a form of programmed cell death called apoptosis, caspases may also function in more subtle… 
Highly Cited
2005
Highly Cited
2005
Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma
The presence of t(4;14)(p16.3;q32.3) in multiple myeloma cells results in dysregulated expression of the fibroblast growth factor… 
2003
2003
Competition between C-C and C-H insertion in prototype transition metal-hydrocarbon reactions.
The competition between C-C and C-H insertion in model transition-metal reactions with cyclopropane and propene (C3H6) was… 
Highly Cited
2003
Highly Cited
2003
Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line
Many apoptotic pathways culminate in the activation of caspase cascades usually triggered by the apical caspases-8 or -9. We… 
2002
2002
MAPK signaling is involved in camptothecin-induced cell death.
2000
2000
Apoptosis Induced by the Nuclear Death Domain Protein p84N5 Is Associated with Caspase-6 and NF-κB Activation*
Although the mechanisms involved in responses to extracellular or mitochondrial apoptotic signals have received considerable… 
Highly Cited
1998
Highly Cited
1998
Investigation of glucocorticoid-induced apoptotic pathway: Processing of Caspase-6 but not Caspase-3
Glucocorticoids (GCs) are essential therapeutic reagents for the treatment of lymphomas and leukemias. GCs cause cell death in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)