Skip to search formSkip to main contentSkip to account menu

CASP4 protein, human

Known as: CASP-4, caspase 4, apoptosis-related cysteine protease protein, human, ICH-2 protein, human 
Caspase-4 (377 aa, ~43 kDa) is encoded by the human CASP4 gene. This protein plays a role in both proteolysis and apoptosis.
National Institutes of Health

Related topics

Related topics

30 relations
ApoptosisCASP2 protein, humanCASP4 geneCASP4 wt Allele

Broader (2)

Caspases, InitiatorCysteine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Lipopolysaccharides-Induced Suppression of Innate-Like B Cell Apoptosis Is Enhanced by CpG Oligodeoxynucleotide and Requires Toll-Like Receptors 2 and 4
Innate-like B lymphocytes play an important role in innate immunity in periodontal disease through Toll-like receptor (TLR… 
2014
2014
Asymmetric dimethylarginine triggers macrophage apoptosis via the endoplasmic reticulum stress pathway
Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is emerging as a key contributing… 
2009
2009
Autophagy induced by 2-deoxy-D-glucose suppresses intracellular multiplication of Legionella pneumophila in A/J mouse macrophages
Legionella pneumophila Philadelphia-1 (Lp-1) can grow intracellularly in A/J mouse peritoneal macrophages (A/J Mφ). We previously… 
Highly Cited
2007
Highly Cited
2007
Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways.
2007
2007
Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells.
Dihydroartemisinin (DHA), a semisynthetic derivative of artemisinin isolated from the traditional Chinese herb Artemisia annua… 
2006
2006
Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death.
Review
2005
Review
2005
In vitro activation of CPP 32 and Mch 3 by Mch 4 , a novel human apoptotic cysteine protease containing two FADD-like domains ( granzyme B / Mch 2 / protease cascade / FAS / APO-I-receptor )
Emerging evidence suggests that an amplifiable protease cascade consisting of multiple aspartatespecific cysteine proteases… 
2005
2005
Cleavage of p 53-Vimentin Complex Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts
  • 2005
  • Corpus ID: 8131658
Rheumatoid arthritis synovial fibroblasts (RASFs) contribute to arthritic cartilage degradation. Although RASFs are normally… 
2003
2003
Induction of apoptosis by combined treatment with differentiation-inducing agents and interferon-alpha in human lung cancer cells.
BACKGROUND Differentiation-inducing agents for myeloid leukemic cells, such as dimethyl sulfoxide (DMSO), Na-butyrate and… 
1997
1997
Experimentelle Untersuchungen zur Einheilung und Antigenität von sterilisierten Knochentransplantaten
Summary. The aim of our study was to observe the incorporation and induced immune response of sterilized bone allografts. We… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)