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cGMP biosynthetic process

Known as: cGMP formation, cGMP biosynthesis, cGMP anabolism 
The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate. [ISBN:0198506732]
National Institutes of Health

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guanylate cyclase activity
negative regulation of cGMP biosynthetic process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Prolonged uterine artery nitric oxide synthase inhibition modestly alters basal uteroplacental vasodilation in the last third of ovine pregnancy.
Mechanisms regulating uteroplacental blood flow (UPBF) in pregnancy remain unclear, but they likely involve several integrated… 
Highly Cited
2010
Highly Cited
2010
The Critical Role of Nitric Oxide Signaling, via Protein S-Guanylation and Nitrated Cyclic GMP, in the Antioxidant Adaptive Response*
A nitrated guanine nucleotide, 8-nitroguanosine 3′,5′-cyclic monophosphate (8-nitro-cGMP), is formed via nitric oxide (NO) and… 
Highly Cited
2003
Highly Cited
2003
Soluble guanylyl cyclase activator YC-1 inhibits human neutrophil functions through a cGMP-independent but cAMP-dependent pathway.
3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1), a novel type of soluble guanylyl cyclase (sGC) activator, is useful in… 
Highly Cited
2000
Highly Cited
2000
nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle.
Nitric oxide (NO) from Ca(2+)-dependent neuronal nitric oxide synthase (nNOS) in skeletal muscle fibers may modulate vascular… 
Highly Cited
2000
Highly Cited
2000
NO‐mediated cGMP synthesis in cholinergic neurons in the rat forebrain: effects of lesioning dopaminergic or serotonergic pathways on nNOS and cGMP synthesis
Nitric oxide synthase (NOS) activity and NO‐mediated cGMP synthesis were studied in the rat forebrain of control animals and… 
Highly Cited
1998
Highly Cited
1998
G protein-dependent activation of smooth muscle eNOS via natriuretic peptide clearance receptor.
In gastrointestinal smooth muscle, the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase… 
Highly Cited
1995
Highly Cited
1995
Serotonin 5‐HT2C Receptor Stimulates Cyclic GMP Formation in Choroid Plexus
Abstract: The serotonin 5‐HT2C receptor (formerly designated the 5‐HT1C receptor) of the choroid plexus triggers phosphoinositide… 
Highly Cited
1994
Highly Cited
1994
Modulation of platelet function by reactive oxygen metabolites.
Reactive oxygen metabolites have been reported to affect platelet aggregation. However, this phenomenon is still poorly… 
1992
1992
Characterization of some biochemical properties of bradykinin-induced cAMP and cGMP formation in guinea pig ileum.
One of the receptor-mediated events, cyclic nucleotide, i.e. cAMP and cGMP formation induced by bradykinin in guinea pig ileum… 
Highly Cited
1990
Highly Cited
1990
Interleukin 1 and tumor necrosis factor stimulate cGMP formation in rat renal mesangial cells
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