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Anti-inflammatory principles from Cordyceps sinensis.
Chemical investigation of the bioactive fractions of the mycelia of Cordyceps sinensis has resulted in the identification of 50 compounds, including five constituents, cordysinins A-E (1-5), reported from a natural source for the first time.
Constituents of the roots of Clausena lansium and their potential anti-inflammatory activity.
Eight new carbazole alkaloids, claulamines C (1), D (2), and E (5) and clausenalines B-F (3, 4, 6-8), four new coumarins, clausemarins A-D (9-12), and 43 known compounds were isolated from the roots…
Neutrophils in Psoriasis
- Chih-Chao Chiang, Wei-Jen Cheng, M. Kořínek, Cheng-Yu Lin, T. Hwang
- Medicine, BiologyFront. Immunol.
- 9 October 2019
An overview on the recent advances in understanding the role of neutrophils in the pathophysiology of psoriasis, including the effects of respiratory burst, degranulation, and neutrophil extracellular trap formation on psoriatic immunity and the clinical relationships is provided.
3-Methyl-4,5-dihydro-oxepine, polyoxygenated seco-cyclohexenes and cyclohexenes from Uvaria flexuosa and their anti-inflammatory activity.
1,5-Diphenylpent-3-en-1-ynes and methyl naphthalene carboxylates from Lawsonia inermis and their anti-inflammatory activity.
Cisplatin encapsulated in phosphatidylethanolamine liposomes enhances the in vitro cytotoxicity and in vivo intratumor drug accumulation against melanomas.
Sirtinol Inhibits Neutrophil Elastase Activity and Attenuates Lipopolysaccharide-Mediated Acute Lung Injury in Mice
- Y. Tsai, Huang-Ping Yu, Wen-yi Chang, Fu-Chao Liu, Zhen-Cheng Huang, T. Hwang
- Medicine, BiologyScientific reports
- 10 February 2015
It is indicated that sirtinol has anti-inflammatory effects through direct inhibition of HNE activity and attenuates HNE-induced and LPS-mediated tissue or organ injury in vivo and is a novel HNE inhibitor.
Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy.
Intracellular Glutathione Depletion by Oridonin Leads to Apoptosis in Hepatic Stellate Cells
- Liang-Mou Kuo, C. Kuo, Chen-Yu Lin, Min-Fa Hung, Jiann-Jong Shen, T. Hwang
- Biology, ChemistryMolecules
- 1 March 2014
Investigation of the apoptotic effects of 7,20-epoxy-ent-kaurane (oridonin), a diterpenoid isolated from Rabdosia rubescens, and its underlying mechanisms were investigated in rat HSC cell line, HSC-T6 found that oridonin inhibited cell viability of HSC -T6 in a concentration-dependent manner.
Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae.
Eight new compounds, including four new neolignans and a new chromene, have been isolated from the stem wood of Zanthoxylum avicennae and the structures of these new compounds were determined through spectroscopic and MS analyses.