beta-Globins

Known as: beta Globins, beta-Globin, beta Globin 
Members of the beta-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 11. They include epsilon-globin, gamma-globin, delta… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Three-dimensional organization of a gene locus is important for its regulation, as recently demonstrated for the beta-globin… (More)
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Highly Cited
2003
Highly Cited
2003
Efficient transcription of genes requires a high local concentration of the relevant trans-acting factors. Nuclear… (More)
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Highly Cited
2002
Highly Cited
2002
Eukaryotic transcription can be regulated over tens or even hundreds of kilobases. We show that such long-range gene regulation… (More)
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Highly Cited
2001
Highly Cited
2001
Methylation of histones at specific residues plays an important role in transcriptional regulation. Chromatin immunoprecipitation… (More)
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Highly Cited
2000
Highly Cited
2000
The stable introduction of a functional beta-globin gene in haematopoietic stem cells could be a powerful approach to treat beta… (More)
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Highly Cited
1997
Highly Cited
1997
We have identified novel nuclear transcripts in the human beta-globin locus using nuclear run-on analysis in erythroid cell lines… (More)
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Highly Cited
1997
Highly Cited
1997
Insulators, first identified in Drosophila, are DNA sequence elements that shield a promoter from nearby regulatory elements. We… (More)
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Highly Cited
1994
Highly Cited
1994
Hypersensitive site 2 located in the beta-globin locus control region confers high levels of expression to the genes of the beta… (More)
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Highly Cited
1994
Highly Cited
1994
The distribution of core histone acetylation across the chicken beta-globin locus has been mapped in 15 day chicken embryo… (More)
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Highly Cited
1993
Highly Cited
1993
We have characterized an element near the 5' boundary of the chicken beta-globin domain that insulates a reporter gene from the… (More)
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