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Hemoglobin Subunit Beta

Known as: Beta-Globin, Hemoglobin Beta Chain 
Hemoglobin subunit beta (147 aa, ~16 kDa) is encoded by the human HBB1 gene. This protein plays a role in the transport of oxygen to tissues of the… 
National Institutes of Health

Related topics

Related topics

10 relations
Cellular MembraneCooley's anemiaErythrocytesHBB gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element.
Effective gene therapy for beta-thalassemia major (beta-TM) requires consistent, high expression of human beta-globin (hbeta… 
Highly Cited
1997
Highly Cited
1997
Posttranscriptional regulation of urokinase receptor mRNA: identification of a novel urokinase receptor mRNA binding protein in human mesothelioma cells
Treatment of human pleural mesothelioma (MS-1) cells with phorbol myristate acetate (PMA) and cycloheximide results in 17- and 10… 
Highly Cited
1994
Highly Cited
1994
Multiple instability-regulating sites in the 3' untranslated region of the urokinase-type plasminogen activator mRNA
In LLC-PK1 cells urokinase-type plasminogen activator (uPA) mRNA has a short half-life. It is stabilized by inhibition of protein… 
Highly Cited
1990
Highly Cited
1990
Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints.
Highly Cited
1989
Highly Cited
1989
Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.
Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human… 
Highly Cited
1987
Highly Cited
1987
OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts.
We have developed a vector, OVEC ("oligonucleotide vector") to study DNA sequences involved in the regulation of transcription in… 
Highly Cited
1985
Highly Cited
1985
Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis.
The melting behavior of a DNA fragment carrying the mouse beta maj-globin promoter was investigated as a means of establishing… 
Highly Cited
1982
Highly Cited
1982
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.
We report the construction of a bovine papillomavirus (BPV)-derived recombinant plasmid that propagates as an extrachromosomal… 
Highly Cited
1982
Highly Cited
1982
Duplication followed by deletion accounts for the structure of an Indian deletion beta (0)-thalassemia gene.
Nucleotide sequence analysis of a cloned deletion beta-globin gene from a patient with beta(0)-thalassemia demonstrates a 619… 
Highly Cited
1977
Highly Cited
1977
Molecular evolution of human and rabbit beta-globin mRNAs.
The primary structures of human and rabbit beta-globin mRNAs are compared. Using as a standard the extent of nucleotide… 
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