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Hemoglobin Subunit Beta
Known as:
Beta-Globin
, Hemoglobin Beta Chain
Hemoglobin subunit beta (147 aa, ~16 kDa) is encoded by the human HBB1 gene. This protein plays a role in the transport of oxygen to tissues of the…
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National Institutes of Health
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Related topics
Related topics
10 relations
Cellular Membrane
Cooley's anemia
Erythrocytes
HBB gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element.
P. Arumugam
,
J. Scholes
,
N. Perelman
,
P. Xia
,
J. Yee
,
P. Malik
Molecular Therapy
2007
Corpus ID: 36654997
Effective gene therapy for beta-thalassemia major (beta-TM) requires consistent, high expression of human beta-globin (hbeta…
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Highly Cited
1997
Highly Cited
1997
Posttranscriptional regulation of urokinase receptor mRNA: identification of a novel urokinase receptor mRNA binding protein in human mesothelioma cells
S. Shetty
,
A. Kumar
,
S. Idell
Molecular and Cellular Biology
1997
Corpus ID: 21404865
Treatment of human pleural mesothelioma (MS-1) cells with phorbol myristate acetate (PMA) and cycloheximide results in 17- and 10…
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Highly Cited
1994
Highly Cited
1994
Multiple instability-regulating sites in the 3' untranslated region of the urokinase-type plasminogen activator mRNA
R. Nanbu
,
P. Menoud
,
Yoshikuni Nagamine
Molecular and Cellular Biology
1994
Corpus ID: 24576161
In LLC-PK1 cells urokinase-type plasminogen activator (uPA) mRNA has a short half-life. It is stabilized by inhibition of protein…
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Highly Cited
1990
Highly Cited
1990
Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints.
P. Henthorn
,
O. Smithies
,
D. Mager
Genomics
1990
Corpus ID: 7598473
Highly Cited
1989
Highly Cited
1989
Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.
Peter T. Curtin
,
Depei Liu
,
Wen Liu
,
JudyC. Chang
,
Yuet Wai Kan
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 6298422
Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human…
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Highly Cited
1987
Highly Cited
1987
OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts.
Gunnar Westin
,
Thomas Gerster
,
Michael M. Müller
,
Gotthold Schaffner
,
Walter Schaffner
Nucleic Acids Research
1987
Corpus ID: 43790918
We have developed a vector, OVEC ("oligonucleotide vector") to study DNA sequences involved in the regulation of transcription in…
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Highly Cited
1985
Highly Cited
1985
Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis.
R. Myers
,
S. Fischer
,
T. Maniatis
,
L. Lerman
Nucleic Acids Research
1985
Corpus ID: 15756568
The melting behavior of a DNA fragment carrying the mouse beta maj-globin promoter was investigated as a means of establishing…
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Highly Cited
1982
Highly Cited
1982
Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.
D. DiMaio
,
R. Treisman
,
T. Maniatis
Proceedings of the National Academy of Sciences…
1982
Corpus ID: 35510688
We report the construction of a bovine papillomavirus (BPV)-derived recombinant plasmid that propagates as an extrachromosomal…
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Highly Cited
1982
Highly Cited
1982
Duplication followed by deletion accounts for the structure of an Indian deletion beta (0)-thalassemia gene.
R. Spritz
,
Stuart H. Orkin
Nucleic Acids Research
1982
Corpus ID: 31621075
Nucleotide sequence analysis of a cloned deletion beta-globin gene from a patient with beta(0)-thalassemia demonstrates a 619…
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Highly Cited
1977
Highly Cited
1977
Molecular evolution of human and rabbit beta-globin mRNAs.
F. Kafatos
,
A. Efstratiadis
,
B. Forget
,
S. Weissman
Proceedings of the National Academy of Sciences…
1977
Corpus ID: 37645895
The primary structures of human and rabbit beta-globin mRNAs are compared. Using as a standard the extent of nucleotide…
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