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Hemoglobin Subunit Beta

Known as: Beta-Globin, Hemoglobin Beta Chain 
Hemoglobin subunit beta (147 aa, ~16 kDa) is encoded by the human HBB1 gene. This protein plays a role in the transport of oxygen to tissues of the… Expand
National Institutes of Health

Related topics

Related topics

10 relations
Cellular MembraneCooley's anemiaErythrocytesHBB gene
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
An important role of Nrf2-ARE pathway in the cellular defense mechanism.
  • J. Lee, J. Johnson
  • Journal of biochemistry and molecular biology
  • 2004
    • Corpus ID: 1201784
The antioxidant responsive element (ARE) is a cis-acting regulatory element of genes encoding phase II detoxification enzymes and… Expand
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Highly Cited
2000
Highly Cited
2000
Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods.
Four quantitative reverse transcription-PCR (RT-PCR) methods were compared to evaluate the time course of mRNA formation and… Expand
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Highly Cited
1999
Highly Cited
1999
The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators
An insulator is a DNA sequence that can act as a barrier to the influences of neighboring cis-acting elements, preventing gene… Expand
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Highly Cited
1995
Highly Cited
1995
The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation.
Labile mRNAs that encode cytokine and immediate-early gene products often contain AU-rich sequences within their 3' untranslated… Expand
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Highly Cited
1990
Highly Cited
1990
Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation
The ubiquitous Oct-1 and lymphoid Oct-2 POU homeodomain transcription factors bind to the same DNA sequence but differ in their… Expand
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Highly Cited
1989
Highly Cited
1989
Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes.
Denaturing gradient gel electrophoresis (DGGE) can be used to distinguish two DNA molecules that differ by as little as a single… Expand
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Highly Cited
1986
Highly Cited
1986
Direct cloning and sequence analysis of enzymatically amplified genomic sequences.
A method is described for directly cloning enzymatically amplified segments of genomic DNA into an M13 vector for sequence… Expand
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Highly Cited
1985
Highly Cited
1985
Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis.
Duplex DNA fragments differing by single base substitutions can be separated by electrophoresis in denaturing gradient… Expand
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Highly Cited
1983
Highly Cited
1983
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II
A new fractionation procedure separates a whole-cell HeLa extract into three components required for accurate in vitro… Expand
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Highly Cited
1978
Highly Cited
1978
Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.
  • Y. Kan, A. Dozy
  • Proceedings of the National Academy of Sciences…
  • 1978
    • Corpus ID: 42123584
Restriction endonuclease mapping of the human globin genes revealed a genetic variation in a Hpa I recognition site about 5000… Expand
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