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benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

Known as: Z-VAD-FMK, ZVAD-fluoromethylketone, ZVAD-FMK 
 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

Ac-ZVAD-FMKFK 009

Broader (3)

Amino Acid Chloromethyl KetonesCaspase InhibitorsNeuroprotective Agents

Papers overview

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2018
2018
Loss of Microglial Parkin Inhibits Necroptosis and Contributes to Neuroinflammation
Parkin is an E3 ubiquitin ligase involved in Parkinson’s disease (PD). Necroptosis is a regulated form of cell death that depends… Expand
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2018
2018
Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo.
The increase in multidrug resistance among colon cancer cells presents a challenge for the development of effective therapies… Expand
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2011
2011
Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma
PURPOSE We recently demonstrated that molecular therapy using aminoglycosides can overcome the underlying genetic defect in two… Expand
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2010
2010
Anti-inflammatory activity of PYNOD and its mechanism in humans and mice.
Many members of the nucleotide-binding and oligomerization domain (NOD)- and leucine-rich-repeat-containing protein (NLR) family… Expand
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2009
2009
Structural basis of caspase-3 substrate specificity revealed by crystallography, enzyme kinetics, and computational modeling
Caspase-3 is a cysteine protease that hydrolyzes diverse intracellular proteins during programmed cell death (known as apoptosis… Expand
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2009
2009
E005 Microparticles from T lymphocytes reduce actinomycin-D induced apoptosis in human endothelial cells
Recent studies have demonstrated that microparticles (MPs) generated from T lymphocytes undergoing both activation and apoptosis… Expand
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2004
2004
In vitro cytotoxicity of orthodontic archwires in cortical cell cultures.
There have been a number of studies regarding the toxicity of orthodontic archwires, but little is known concerning the mechanism… Expand
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Highly Cited
2000
Highly Cited
2000
Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase.
c-Jun N-terminal protein kinase (JNK) and p38 mitogen-activated protein kinase are activated by stress and are implicated in… Expand
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2000
2000
The Tyrosine Kinase Inhibitor CGP 57148 ( ST 1 571 ) Induces Apoptosis in BCR-ABL-positive Cells by Down-Regulating BCL-X 1
CGP 57148 is a potent inhibitor of the ABL protein tyrosine kinase and a promising new compound for the treatment of a variety of… Expand
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Highly Cited
1997
Highly Cited
1997
Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis.
Neuronal apoptosis occurs during nervous system development and after pathological insults to the adult nervous system… Expand
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