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benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

Known as: Z-VAD-FMK, ZVAD-fluoromethylketone, ZVAD-FMK 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

Ac-ZVAD-FMKFK 009

Broader (3)

Amino Acid Chloromethyl KetonesCaspase InhibitorsNeuroprotective Agents

Papers overview

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2018
2018
Loss of Microglial Parkin Inhibits Necroptosis and Contributes to Neuroinflammation
Parkin is an E3 ubiquitin ligase involved in Parkinson’s disease (PD). Necroptosis is a regulated form of cell death that depends… 
2018
2018
Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo
Abstract The increase in multidrug resistance among colon cancer cells presents a challenge for the development of effective… 
2011
2011
Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma
Purpose We recently demonstrated that molecular therapy using aminoglycosides can overcome the underlying genetic defect in two… 
Highly Cited
2010
Highly Cited
2010
Anti-Inflammatory Activity of PYNOD and Its Mechanism in Humans and Mice
Many members of the nucleotide-binding and oligomerization domain (NOD)- and leucine-rich-repeat–containing protein (NLR) family… 
2009
2009
E005 Microparticles from T lymphocytes reduce actinomycin-D induced apoptosis in human endothelial cells
2004
2004
In vitro cytotoxicity of orthodontic archwires in cortical cell cultures.
There have been a number of studies regarding the toxicity of orthodontic archwires, but little is known concerning the mechanism… 
Highly Cited
2000
Highly Cited
2000
Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein Kinase
c-Jun N-terminal protein kinase (JNK) and p38 mitogen-activated protein kinase are activated by stress and are implicated in… 
2000
2000
The Tyrosine Kinase Inhibitor CGP 57148 ( ST 1 571 ) Induces Apoptosis in BCR-ABL-positive Cells by Down-Regulating BCL-X 1
CGP 57148 is a potent inhibitor of the ABL protein tyrosine kinase and a promising new compound for the treatment of a variety of… 
Highly Cited
1997
Highly Cited
1997
Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis
Neuronal apoptosis occurs during nervous system development and after pathological insults to the adult nervous system… 
1997
1997
Inhibition of the interleukin-1β converting enzyme family rescues neurons from apoptotic death
The interleukin-1β converting enzyme (ICE) family of cysteine proteases has been implicated in apoptosis. This study tested the… 
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