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ascididemin

Known as: 9H-quino(4,3,2-de)(1,10)phenanthroline-9-one 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

AlkaloidsPhenanthrolinesQuinolines

Papers overview

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2012
2012
Total synthesis of ascididemin via anionic cascade ring closure.
A new and convergent synthesis of ascididemin is presented. Using an anionic cascade ring closure as the key step, this natural… 
2010
2010
Structures and antimicrobial activities of pyridoacridine alkaloids isolated from different chromotypes of the ascidian Cystodytes dellechiajei.
Three new pentacyclic alkaloids were isolated from different chromotypes of the western Mediterranean ascidian Cystodytes… 
2004
2004
Synthesis and in vitro antitumor activity of ring C and D-substituted phenanthrolin-7-one derivatives, analogues of the marine pyridoacridine alkaloids ascididemin and meridine.
Highly Cited
2003
Highly Cited
2003
Mechanism of ascididemin-induced cytotoxicity.
Some marine animals are rich sources of unique polycyclic aromatic alkaloids that are cytotoxic against tumor cell lines and… 
2003
2003
Antiparasitic activity of marine pyridoacridone alkaloids related to the ascididemins.
A series of pyridoacridone alkaloids, including the marine alkaloid ascididemin were tested in vitro for antiparasitic activity… 
2003
2003
Apoptosis Induced by the Alkaloid Sampangine in HL‐60 Leukemia Cells
Abstract: Sampangine, a plant‐derived copyrine alkaloid extracted from the stem bark of Cananga odorata, primarily exhibits… 
2002
2002
Three new pyridoacridine type alkaloids from a singaporean ascidian.
Two new pyridoacridine alkaloids, kuanoniamines E and F, and a new ring-opened pyridoacridine alkaloid, subarine, were isolated… 
Highly Cited
2000
Highly Cited
2000
Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells.
1997
1997
Plakinidine D, a new pyrroloacridine alkaloid from two ascidians of the genus Didemnum.
A previously undescribed red Didemnum sp. collected in Indonesia contained a novel pyrroloacridine, plakinidine D (4), along with… 
1995
1995
Binding to DNA and cytotoxic evaluation of ascididemin, the major alkaloid from the Mediterranean ascidian Cystodytes dellechiajei.
The isolation of ascididemin from the Mediterranean ascidian Cystodytes dellechiajei is described. This alkaloid consists of a… 
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