artesunate

Known as: dihydroqinghasu hemsuccinate, 4-oxo-4-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy}butanoic acid, butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester 
A water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Plasmodium falciparum resistance to artemisinins, the first line treatment for malaria worldwide, has been reported in… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Artemisinin-based combination therapies are the recommended first-line treatments of falciparum malaria in all… (More)
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Review
2008
Review
2008
Traditional Chinese medicine commands a unique position among all traditional medicines because of its 5000 years of history. Our… (More)
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Highly Cited
2006
Highly Cited
2006
June 2006 | Volume 3 | Issue 6 | e197 Falciparum malaria kills, and it particularly kills the rural poor. Artemisinin derivatives… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND In the treatment of severe malaria, intravenous artesunate is more rapidly acting than intravenous quinine in terms of… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Increasing drug resistance limits the choice of efficacious chemotherapy against Plasmodium falciparum malaria in… (More)
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Highly Cited
2001
Highly Cited
2001
Artesunate is a key antimalarial drug in the treatment of multidrug-resistant Plasmodium falciparum malaria in southeast Asia. We… (More)
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Highly Cited
2001
Highly Cited
2001
Artesunate (ART) is a semi-synthetic derivative of artemisinin, the active principle of the Chinese herb Artemisia annua. ART… (More)
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Highly Cited
2001
Highly Cited
2001
Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by… (More)
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