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artesunate

Known as: dihydroqinghasu hemsuccinate, 4-oxo-4-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy}butanoic acid, butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester 
A water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential… 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (3)

AmebicidesAntimalarialsArtemisinins

Narrower (4)

Malacefartesunic acidmalartinsodium artesunate
WHO Adverse Reaction Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Enhanced delivery of artemisinin and its analogues to cancer cells by their adducts with human serum transferrin.
Highly Cited
2011
Highly Cited
2011
Interaction between Artemether-Lumefantrine and Nevirapine-Based Antiretroviral Therapy in HIV-1-Infected Patients
ABSTRACT Artemether-lumefantrine and nevirapine-based antiretroviral therapy (ART) are the most commonly recommended first-line… 
Highly Cited
2010
Highly Cited
2010
Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.
Artesunate, a semi-synthetic derivative of artemisinin, is an effective and safe anti-malaria drug, which also exhibits activity… 
2009
2009
Quantification of artemisinin in human plasma using liquid chromatography coupled to tandem mass spectrometry
Review
2005
Review
2005
Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins.
Highly Cited
2005
Highly Cited
2005
Short-Course Regimens of Artesunate-Fosmidomycin in Treatment of Uncomplicated Plasmodium falciparum Malaria
ABSTRACT Fosmidomycin is effective against malaria, but it needs to be given for ≥4 days when used alone. We conducted a study of… 
2005
2005
Curdlan sulphate in human severe/cerebral Plasmodium falciparum malaria.
Highly Cited
2004
Highly Cited
2004
Adherence to antimalarial combination therapy with sulfadoxine-pyrimethamine and artesunate in rural Tanzania.
Artemisinin-containing antimalarial combination therapies are recommended to confront drug-resistant Plasmodium falciparum… 
Highly Cited
2003
Highly Cited
2003
Efficacy of amodiaquine alone and combined with sulfadoxine-pyrimethamine and of sulfadoxine pyrimethamine combined with artesunate.
The safety and the efficacy of amodiaquine (AQ) alone, AQ plus sulfadoxine-pyrimethamine (SP) (AQ plus SP), and artesunate (ART… 
2002
2002
Assessment of the neurotoxicity of oral dihydroartemisinin in mice.
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