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acetaminophen glucuronide

Known as: 4-acetamidophenol glucuronide, beta-D-Glucopyranosiduronic acid, 4-(acetylamino)phenyl, paracetamol glucuronide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2016
051019752016

Related topics

Related topics

2 relations

Broader (1)

Acetaminophen
analogs & derivatives

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
acetaminophen glucuronide
Acetaminophen
analogs & derivatives

Papers overview

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Highly Cited
2009
Highly Cited
2009
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism.
We provide a demonstration in humans of the principle of pharmacometabonomics by showing a clear connection between an individual… (More)
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2008
2008
Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats.
Renal and intestinal disposition of acetaminophen glucuronide (APAP-GLU), a common substrate for multidrug resistance-associated… (More)
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Highly Cited
2006
Highly Cited
2006
Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and…
Although glucuronide and sulfate conjugates of many drugs and endogenous compounds undergo appreciable hepatic basolateral… (More)
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2002
2002
Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment.
Previous studies have demonstrated that phenobarbital (PB) significantly impairs the biliary excretion of acetaminophen… (More)
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Highly Cited
2000
Highly Cited
2000
Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats.
Previous studies have demonstrated that phenobarbital treatment impairs the biliary excretion of acetaminophen glucuronide (AG… (More)
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Highly Cited
2000
Highly Cited
2000
Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus.
We tested the hypothesis that a lack of suppression of glucagon causes postprandial hyperglycemia in subjects with type 2… (More)
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1994
1994
The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes.
The impact of gender, use of oral contraceptive steroids (OCS), coffee consumption and of smoking on the metabolism of sparteine… (More)
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1992
1992
Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome.
Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of… (More)
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1991
1991
Impaired sulphation of phenol by the colonic mucosa in quiescent and active ulcerative colitis.
Substantial amounts of phenols are produced in the human colon by bacterial fermentation of protein. In the colonic mucosa of… (More)
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1975
1975
Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion.
The purpose of this study was to determine if certain physiologic parameters (plasma bilirubin concentration and urinary… (More)
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