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UDP-glucuronosyltransferase activity
Known as:
UDPGT activity
, GT activity
, uridine diphosphoglucuronyltransferase activity
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Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. [EC:2.4.1.17]
National Institutes of Health
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Related topics
Related topics
3 relations
Glucuronosyltransferase
negative regulation of glucuronosyltransferase activity
positive regulation of glucuronosyltransferase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Modulation of UDP-glucuronosyltransferase activity by endogenous compounds.
Y. Ishii
,
A. Nurrochmad
,
H. Yamada
Drug Metabolism and Pharmacokinetics
2010
Corpus ID: 12920484
Glucuronidation is one of the major pathways of metabolism of endo- and xenobiotics. UDP-Glucuronosyltransferase (UGT)-catalyzed…
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2007
2007
Glucuronidation of Antiallergic Drug, Tranilast: Identification of Human UDP-Glucuronosyltransferase Isoforms and Effect of Its Phase I Metabolite
M. Katoh
,
Tomohito Matsui
,
T. Yokoi
Drug Metabolism And Disposition
2007
Corpus ID: 10466917
Tranilast is an oral antiallergic agent widely used in Japan. Recently, in Western populations, hyperbilirubinemia induced by…
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1996
1996
Evidence for an UDP-glucuronic acid/phenol glucuronide antiport in rat liver microsomal vesicles.
G. Bánhegyi
,
L. Braun
,
+4 authors
A. Benedetti
Biochemical Journal
1996
Corpus ID: 10181853
The transport of glucuronides synthesized in the luminal compartment of the endoplasmic reticulum by UDP-glucuronosyltransferase…
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1990
1990
Increased thyroxine turnover after 3,3',4,4',5,5'-hexabromobiphenyl injection and lack of effect on peripheral triiodothyronine production.
P. Spear
,
P. Higueret
,
H. Garcin
Canadian Journal of Physiology and Pharmacology
1990
Corpus ID: 22805244
Juvenile male Wistar rats were injected i.p. with 0, 20, or 40 mg/kg 3,3',4,4',5,5'-hexabromobiphenyl and blood samples collected…
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1985
1985
Separation, purification, and characterization of digitoxigenin-monodigitoxoside UDP-glucuronosyltransferase activity.
L. von Meyerinck
,
B. L. Coffman
,
M. Green
,
R. Kirkpatrick
,
A. Schmoldt
,
T. Tephly
Drug Metabolism And Disposition
1985
Corpus ID: 37085464
Glucuronidation of digitoxigenin-monodigitoxoside was investigated in liver microsomes from spironolactone-induced male Wistar…
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1982
1982
Maximal biliary secretion of bilirubin in the anaesthetized rat: dependence on UDP-glucuronosyltransferase activity.
W. Steenbergen
,
J. Fevery
Clinical science
1982
Corpus ID: 28509977
1. Hepatic bilirubin UDP-glucuronosyl transferase activity in heterozygous Gunn rats (Jj) was only two-thirds of that in the…
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1979
1979
The interaction of styrene oxide with hepatic cytochrome P-450 in vitro and effects of styrene oxide inhalation on xenobiotic biotransformation in mouse liver and kidney.
H. Vainio
,
E. Elovaara
Biochemical Pharmacology
1979
Corpus ID: 37413586
1976
1976
Solid-phase synthesis of drug glucuronides by immobilized glucuronosyltransferase.
C. Fenselau
,
S. Pallante
,
E. Parikh
Journal of Medicinal Chemistry
1976
Corpus ID: 40225851
Rabbit liver glucuronosyltransferase immobilized on beaded agarose has been used to synthesize glucuronic acid conjugates of…
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1973
1973
Induction of an Enzyme in Genetically Deficient Rats after Grafting of Normal Liver
A. B. Mukherjee
,
J. Krasner
Science
1973
Corpus ID: 42837944
Tissue from normal rat livers was grafted onto the livers of rats that were genetically deficient in bilirubin uridine…
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1973
1973
Regulation of microsomal enzymes by phospholipids. VI. Abnormal enzyme-lipid interactions in liver microsomes from Gunn rats.
D. Zakim
,
J. Goldenberg
,
D. Vessey
Biochimica et Biophysica Acta
1973
Corpus ID: 8094421
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