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UDP-glucuronosyltransferase activity

Known as: UDPGT activity, GT activity, uridine diphosphoglucuronyltransferase activity 
Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. [EC:2.4.1.17]
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
The activity, expression and localization of the UDP-glucuronosyltransferases (UGTs) were investigated in human placenta at term… Expand
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Highly Cited
2000
Highly Cited
2000
UDP-glucuronosyltransferases (UGTs) convert dietary constituents, drugs, and environmental mutagens to inactive hydrophilic… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS The contribution of glucuronidation toward human drug metabolism is carried out by the Super gene family of UDP… Expand
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Highly Cited
1998
Highly Cited
1998
Crigler–Najjar syndrome type I is a recessively inherited disorder characterized by severe unconjugated hyperbilirubinemia… Expand
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1998
1998
Our laboratory has characterized androgen metabolism in an androgen-responsive prostate cancer cell line (LNCaP) and showed that… Expand
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1992
1992
Glucuronidation of thyroxine (T4) by liver microsomal UDP-glucuronosyltransferase (UDP-GT) is a predominant pathway by which T4… Expand
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1989
1989
Isolated cryopreserved human liver cells, attached to collagen-coated microcarriers, were injected intraperitoneally into mutant… Expand
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Highly Cited
1986
Highly Cited
1986
Isolated hepatocytes, harvested from normal rat livers by portal vein collagenase perfusion, can be attached to collagen-coated… Expand
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1984
1984
Bilirubin uridine diphosphate-glucuronosyltransferase activity was markedly higher in liver preparations of adult female rats… Expand
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Highly Cited
1979
Highly Cited
1979
UDP-glucuronyltransferase activities towards 2-aminophenol and bilirubin were studied in a total of 70 human subjects, including… Expand
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