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UDP-glucuronosyltransferase activity
Known as:
UDPGT activity
, GT activity
, uridine diphosphoglucuronyltransferase activity
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Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside. [EC:2.4.1.17]
National Institutes of Health
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Related topics
Related topics
3 relations
Glucuronosyltransferase
negative regulation of glucuronosyltransferase activity
positive regulation of glucuronosyltransferase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Glucuronidation of Antiallergic Drug, Tranilast: Identification of Human UDP-Glucuronosyltransferase Isoforms and Effect of Its Phase I Metabolite
M. Katoh
,
Tomohito Matsui
,
T. Yokoi
Drug Metabolism And Disposition
2007
Corpus ID: 10466917
Tranilast is an oral antiallergic agent widely used in Japan. Recently, in Western populations, hyperbilirubinemia induced by…
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1996
1996
Evidence for an UDP-glucuronic acid/phenol glucuronide antiport in rat liver microsomal vesicles.
G. Bánhegyi
,
L. Braun
,
+4 authors
A. Benedetti
Biochemical Journal
1996
Corpus ID: 10181853
The transport of glucuronides synthesized in the luminal compartment of the endoplasmic reticulum by UDP-glucuronosyltransferase…
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1993
1993
A method for the determination of UDP-glucuronosyltransferase activity toward arylcarboxylic acids.
M. Pritchard
,
S. Fournel‐Gigleux
,
G. Siest
,
J. Magdalou
Analytical Biochemistry
1993
Corpus ID: 43751482
A fast and reliable method for the assay of UDP-glucuronosyltransferase (UGT) activity toward aglycones containing a carboxylic…
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1991
1991
Hepatic transport of bilirubin in rats with streptozotocin-induced diabetes.
M. Tuñón
,
P. González
,
L. García-Pardo
,
J. González
Journal of Hepatology
1991
Corpus ID: 3668516
1990
1990
Increased thyroxine turnover after 3,3',4,4',5,5'-hexabromobiphenyl injection and lack of effect on peripheral triiodothyronine production.
P. Spear
,
P. Higueret
,
H. Garcin
Canadian Journal of Physiology and Pharmacology
1990
Corpus ID: 22805244
Juvenile male Wistar rats were injected i.p. with 0, 20, or 40 mg/kg 3,3',4,4',5,5'-hexabromobiphenyl and blood samples collected…
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1988
1988
Biosynthesis of hydroxyl-linked glucuronides of short-chain bile acids by rat liver 3-hydroxysteroid UDP-glucuronosyltransferase.
A. Radominska
,
M. Green
,
P. Zimniak
,
R. Lester
,
T. Tephly
Journal of Lipid Research
1988
Corpus ID: 2982056
Microsomal preparations from livers of Sprague-Dawley rats catalyze the glucuronidation of 3 alpha-hydroxy-5 beta-H (3 alpha, 5…
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1982
1982
Maximal biliary secretion of bilirubin in the anaesthetized rat: dependence on UDP-glucuronosyltransferase activity.
W. Steenbergen
,
J. Fevery
Clinical science
1982
Corpus ID: 28509977
1. Hepatic bilirubin UDP-glucuronosyl transferase activity in heterozygous Gunn rats (Jj) was only two-thirds of that in the…
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1979
1979
The interaction of styrene oxide with hepatic cytochrome P-450 in vitro and effects of styrene oxide inhalation on xenobiotic biotransformation in mouse liver and kidney.
H. Vainio
,
E. Elovaara
Biochemical Pharmacology
1979
Corpus ID: 37413586
1979
1979
Purification and partial characterization of rat liver bilirubin glucuronoside glucuronosyltransferase.
J. Chowdhury
,
N. Chowdhury
,
M. Bhargava
,
I. Arias
Journal of Biological Chemistry
1979
Corpus ID: 28692097
Bilirubin glucuronoside glucuronosyltransferase (EC 2.4.1.95) converts bilirubin monoglucuronide to bilirubin diglucuronide and…
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1976
1976
Solid-phase synthesis of drug glucuronides by immobilized glucuronosyltransferase.
C. Fenselau
,
S. Pallante
,
E. Parikh
Journal of Medicinal Chemistry
1976
Corpus ID: 40225851
Rabbit liver glucuronosyltransferase immobilized on beaded agarose has been used to synthesize glucuronic acid conjugates of…
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