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Diagnosis and management of primary sclerosing cholangitis
Intended for use by physicians, these recommendations suggest preferred approaches to the diagnostic, therapeutic and preventative aspects of care that are intended to be flexible, in contrast to standards of care, which are inflexible policies to be followed in every case. Expand
Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure
The MARS device, and not the Prometheus device, significantly attenuates the hyperdynamic circulation in acute-on-chronic liver failure, presumably by a difference in removal rate of certain vasoactive substances. Expand
The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin
Cytokeratin 7 and CK19 expression, present in hepatic progenitor cells and in cholangiocytes but not in normal hepatocytes, has been reported in some hepatocellular carcinomas, but the incidence and relevance of this expression in HCC in Caucasians is not known. Expand
Bilirubin in clinical practice: a review
  • J. Fevery
  • Medicine
  • Liver international : official journal of the…
  • 1 May 2008
Bilirubin is an endogenous compound that can be toxic under certain conditions but, on the other hand, mild unconjugated hyperbilirubinaemia might protect against cardiovascular diseases and tumourExpand
Screening properties of questionnaires and laboratory tests for the detection of alcohol abuse or dependence in a general practice population.
It is confirmed that conventional laboratory tests are of no use for detecting alcohol abuse or dependence in a primary care setting and the %CDT cannot been used as a screening instrument in this general practice population. Expand
The value of CAGE, CUGE, and AUDIT in screening for alcohol abuse and dependence among college freshmen.
The newly constructed CUGE questionnaire may improve screening efforts in students, compared with existing questionnaires, and is confirmed to be high in college students. Expand
Investigating the Origin and Spread of Hepatitis C Virus Genotype 5a
It is indicated that HCV genotype 5a strains have been spreading independently in Belgium and South Africa for more than 100 years, with a rate of spread characteristic of an epidemic genotype. Expand
Human Embryonic and Rat Adult Stem Cells with Primitive Endoderm-Like Phenotype Can Be Fated to Definitive Endoderm, and Finally Hepatocyte-Like Cells
A protocol that mimics mammalian liver development, to differentiate cells with pluripotent characteristics to hepatocyte-like cells is developed, useful for generating hepatocytes- like cells from rodent and human stem cells, and to gain insight into the early stages of liver development. Expand
Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.
In an analysis of data from individual patients with PSC worldwide, significant variation in clinical course associated with age at diagnosis, sex, and ductal and IBD subtypes is found. Expand
Incidence, Diagnosis, and Therapy of Cholangiocarcinoma in Patients with Primary Sclerosing Cholangitis
If tumors are small or incidental findings, liver transplantation leads to a 3- to 5-year survival rate of 35%. Expand