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Guidelines for the use and interpretation of assays for monitoring autophagy
These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Endoplasmic Reticulum Stress
- G. Bánhegyi, P. Baumeister, Wei Yang
- Biology, MedicineAnnals of the New York Academy of Sciences
- 1 October 2007
The emerging role of ER stress in diverse human pathophysiological conditions such as carcinogenesis and tumor progression, cerebral ischemia, plasma cell maturation and apoptosis, obesity, insulin resistance, and type 2 diabetes is summarized.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms.
Vitamin C: update on physiology and pharmacology
The increasing knowledge of the functions of ascorbate and of its molecular sites of action can mechanistically substantiate a place for asCorbate in the treatment of various diseases.
Cooperativity between 11β-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-phosphate Dehydrogenase in the Lumen of the Endoplasmic Reticulum*
- G. Bánhegyi, A. Benedetti, R. Fulceri, S. Senesi
- Biology, ChemistryJournal of Biological Chemistry
- 25 June 2004
The results demonstrate a close cooperation of the enzymes based on co-localization and the mutual generation of cofactors for each other in rat liver microsomal vesicles.
The Ascorbate-glutathione-α-tocopherol Triad in Abiotic Stress Response
- A. Szarka, B. Tomasskovics, G. Bánhegyi
- BiologyInternational Journal of Molecular Sciences
- 10 April 2012
This work is presenting a review of abiotic stress responses connected to low molecular weight antioxidants, which are capable of chelating metal ions and reducing thus their catalytic activity to form ROS and also scavenge them in plants.
Ascorbate metabolism and its regulation in animals.
Preferential Transport of Glutathione versusGlutathione Disulfide in Rat Liver Microsomal Vesicles*
- G. Bánhegyi, L. Lusini, A. Benedetti
- Biology, ChemistryThe Journal of Biological Chemistry
- 30 April 1999
A bi-directional, saturable transport of glutathione (GSH) was found in rat liver microsomal vesicles, and GSSG entrapped and accumulated in the lumen creates the oxidized state of its redox buffer.
On the role of 4-hydroxynonenal in health and disease.