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- Publications
- Influence
Endoplasmic Reticulum Stress
- G. Bánhegyi, P. Baumeister, +13 authors Wei Yang
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 1 October 2007
Abstract: Stress is the imbalance of homeostasis, which can be sensed even at the subcellular level. The stress‐sensing capability of various organelles including the endoplasmic reticulum (ER) has… Expand
Vitamin C: update on physiology and pharmacology
- J. Mandl, A. Szarka, G. Bánhegyi
- Biology, Medicine
- British journal of pharmacology
- 1 August 2009
Although ascorbic acid is an important water‐soluble antioxidant and enzyme cofactor in plants and animals, humans and some other species do not synthesize ascorbate due to the lack of the enzyme… Expand
Cooperativity between 11β-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-phosphate Dehydrogenase in the Lumen of the Endoplasmic Reticulum*
- G. Bánhegyi, A. Benedetti, R. Fulceri, S. Senesi
- Biology, Medicine
- Journal of Biological Chemistry
- 25 June 2004
The functional coupling of 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase was investigated in rat liver microsomal vesicles. The activity of both enzymes was latent in… Expand
Ascorbate metabolism and its regulation in animals.
- G. Bánhegyi, L. Braun, M. Csala, F. Puskás, J. Mandl
- Chemistry, Medicine
- Free radical biology & medicine
- 1997
This article provides a comprehensive review on ascorbate metabolism in animal cells, especially in hepatocytes. The authors deal with the synthesis and the breakdown of ascorbate as a part of the… Expand
Preferential Transport of Glutathione versusGlutathione Disulfide in Rat Liver Microsomal Vesicles*
- G. Bánhegyi, L. Lusini, +7 authors A. Benedetti
- Chemistry, Medicine
- The Journal of Biological Chemistry
- 30 April 1999
A bi-directional, saturable transport of glutathione (GSH) was found in rat liver microsomal vesicles. GSH transport could be inhibited by the anion transport blockers flufenamic acid and… Expand
The Ascorbate-glutathione-α-tocopherol Triad in Abiotic Stress Response
- A. Szarka, B. Tomasskovics, G. Bánhegyi
- Biology, Medicine
- International journal of molecular sciences
- 10 April 2012
The life of any living organism can be defined as a hurdle due to different kind of stresses. As with all living organisms, plants are exposed to various abiotic stresses, such as drought, salinity,… Expand
On the role of 4-hydroxynonenal in health and disease.
- M. Csala, T. Kardon, +7 authors G. Bánhegyi
- Chemistry, Medicine
- Biochimica et biophysica acta
- 1 May 2015
Polyunsaturated fatty acids are susceptible to peroxidation and they yield various degradation products, including the main α,β-unsaturated hydroxyalkenal, 4-hydroxy-2,3-trans-nonenal (HNE) in… Expand
Lipotoxicity in the liver.
- V. Zámbó, Laura Simon-Szabó, Péter Szelényi, É. Kereszturi, G. Bánhegyi, Miklós Csala
- Biology, Medicine
- World journal of hepatology
- 27 October 2013
Obesity due to excessive food intake and the lack of physical activity is becoming one of the most serious public health problems of the 21(st) century. With the increasing prevalence of obesity,… Expand
The glucose-6-phosphate transporter-hexose-6-phosphate dehydrogenase-11beta-hydroxysteroid dehydrogenase type 1 system of the adipose tissue.
- P. Marcolongo, Simona Piccirella, +6 authors A. Benedetti
- Medicine, Biology
- Endocrinology
- 1 May 2007
11beta-hydroxysteroid dehydrogenase type 1, expressed mainly in the endoplasmic reticulum of adipocytes and hepatocytes, plays an important role in the prereceptorial activation of glucocorticoids.… Expand
Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum
- S. Senesi, M. Csala, +4 authors A. Benedetti
- Biology, Medicine
- Biological chemistry
- 2010
Abstract Hexose-6-phosphate dehydrogenase (H6PD) is a luminal enzyme of the endoplasmic reticulum that is distinguished from cytosolic glucose-6-phosphate dehydrogenase by several features. H6PD… Expand