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Glucuronosyltransferase

Known as: UDP Glucuronosyltransferase, Glucuronyl Transferase, UDP, Transferase, Glucuronic 
A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (21)

7-Hydroxycoumarin UDP GlucuronyltransferaseB3GAT2 protein, humanGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferaseGlcAT-P protein, Drosophila
Glucuronosyl transferases [PK]In BloodProcess of secretionUDP-glucuronosyltransferase activity

Broader (1)

hexosyltransferase

Papers overview

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1985
1985
Furosemide 1-O-acyl glucuronide. In vitro biosynthesis and pH-dependent isomerization to beta-glucuronidase-resistant forms.
A biosynthetic acyl-type glucuronic acid conjugate of furosemide was isolated from in vitro incubation of pregnenolone-16 alpha… 
Highly Cited
1982
Highly Cited
1982
Comparative effects of dietary administration of 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxytoluene on several hepatic enzyme activities in mice and rats.
Effects of feeding mice and rats with 2(3)-tert-butyl-4-hydroxyanisole (BHA) and 3,5-di-tert-butyl-4-hydroxytoluene (BHT), the… 
Highly Cited
1978
Highly Cited
1978
Effect of polycyclic aromatic hydrocarbons on hepatic microsomal enzymes and disposition of methylnaphthalene in rainbow trout in vivo.
1. The effects of 3-methylcholanthrene, 2,3-benzanthracene and beta-naphthoflavone on xenobiotic metabolism in rainbow trout were… 
1977
1977
Studies on the purification of rat liver uridine diphosphate glucuronyltransferase.
1. A stable, more highly purified, preparation of UDP-glucuronyltransferase was obtained than previously reported. 2. Enzyme… 
1974
1974
Morphine metabolism. II. Studies on morphine glucuronyltransferase activity in intestinal microsomes of rats.
Highly Cited
1973
Highly Cited
1973
Drug hydroxylation and glucuronidation in liver microsomes of phenobarbital-treated rats.
  • H. Vainio
  • Xenobiotica; the fate of foreign compounds in…
  • 1973
  • Corpus ID: 31880922
Abstract1. The rise in p-nitroanisole O-demethylase activity in liver microsomes after phenobarbital treatment of rats slightly… 
Highly Cited
1972
Highly Cited
1972
Regulation of microsomal enzymes by phospholipids. V. Kinetic studies of hepatic uridine diphosphate-glucuronyltransferase.
Abstract A bisubstrate kinetic analysis of UDP-glucuronyltransferase (EC 2.4.1.17) has been carried out in forward and reverse… 
Highly Cited
1970
Highly Cited
1970
The effect of phenobarbital on the submicrosomal distribution of uridine diphosphate glucuronyltransferase from rat liver.
1. The detergent Triton X-100 activates UDP glucuronyltransferase from rat liver in vitro six- to seven-fold with p-nitrophenol… 
1968
1968
The submicrosomal distribution of hepatic uridine diphosphate glucuronyltransferases in the rabbit.
1. Rabbit liver microsomes were subfractionated into rough- and smooth-surfaced types, and glucuronyltransferase activity in each… 
Highly Cited
1966
Highly Cited
1966
The formation of bilirubin and p-nitrophenyl glucuronides by rabbit liver.
1. Glucuronide formation of bilirubin and p-nitrophenol in vitro with excess of UDP-glucuronic acid by UDP-glucuronyltransferase…