UBE3A wt Allele

Known as: FLJ26981, ANCR, EPVE6AP 
Human UBE3A wild-type allele is located within 15q11-q13 and is approximately 102 kb in length. This allele, which encodes ubiquitin-protein ligase… (More)

Topic mentions per year

Topic mentions per year

1994-2018
0519942018

Papers overview

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2005
2005
The function of the human papillomavirus (HPV) E6 protein that is most clearly linked to carcinogenesis is the targeted… (More)
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Highly Cited
2003
Highly Cited
2003
Ubiquitin ligases (E3) select proteins for ubiquitylation, a modification that directs altered subcellular trafficking and/or… (More)
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Highly Cited
2000
Highly Cited
2000
The high-risk human papillomavirus (HPV) E6 proteins stimulate the ubiquitination and degradation of p53, dependent on the E6AP… (More)
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Highly Cited
1999
Highly Cited
1999
In this study, we found that the E6-associated protein (E6-AP/UBE3A) directly interacts with and coactivates the transcriptional… (More)
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Highly Cited
1999
Highly Cited
1999
The transforming proteins of the small DNA tumor viruses, simian virus 40 (SV40), adenovirus, and human papillomavirus (HPV… (More)
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Highly Cited
1999
Highly Cited
1999
The human papilloma virus E6-associated protein (E6AP) functions as a ubiquitin protein ligase (E3) in the E6-mediated… (More)
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Highly Cited
1998
Highly Cited
1998
The E6 protein encoded by the oncogenic human papillomaviruses (HPVs) targets p53 for ubiquitin-dependent proteolysis. E6… (More)
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Highly Cited
1998
Highly Cited
1998
Ubiquitin ligases are generally assumed to play a major role in substrate recognition and thus provide specificity to a… (More)
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Highly Cited
1995
Highly Cited
1995
E6-AP is a 100-kDa cellular protein that interacts with the E6 protein of the cancer-associated human papillomavirus types 16 and… (More)
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Highly Cited
1994
Highly Cited
1994
The E6 protein of the oncogenic human papillomavirus types 16 and 18 facilitates the rapid degradation of the tumor-suppressor… (More)
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