Protein Degradation, Metabolic

Known as: Protein Degradation, Protein Turnover, protein catabolism 
The normal "downside" of protein steady state metabolism in cells, involving conjugation, transport, oxidation, and proteolysis; not to be confuse… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The ubiquitin proteasome pathway is responsible for most of the protein degradation in mammalian cells. Rates of degradation by… (More)
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Highly Cited
2005
Highly Cited
2005
Spinal muscular atrophy (SMA) is an autosomal recessive disorder in humans which results in the loss of motor neurons. It is… (More)
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Highly Cited
2005
Highly Cited
2005
The giant sarcomeric protein titin contains a protein kinase domain (TK) ideally positioned to sense mechanical load. We… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Transcription factor Nrf2 regulates the expression of a set of detoxifying and anti-oxidant enzyme genes. Several… (More)
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Highly Cited
2002
Highly Cited
2002
One hypothesis for the etiology of Parkinson's disease (PD) is that subsets of neurons are vulnerable to a failure in proteasome… (More)
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Highly Cited
2001
Highly Cited
2001
Transcript regulation in response to high salinity was investigated for salt-tolerant rice (var Pokkali) with microarrays… (More)
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Review
1998
Review
1998
Insulin degradation is a regulated process that plays a role in controlling insulin action by removing and inactivating the… (More)
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Review
1998
Review
1998
Bcl-2 family proteins serve as critical regulators of pathways involved in apoptosis, acting to either inhibit or promote cell… (More)
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Highly Cited
1995
Highly Cited
1995
The rates of protein synthesis and degradation and of amino acid transport were determined in the leg muscle of untrained… (More)
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Highly Cited
1975
Highly Cited
1975
Incorporation of radiolabeled precursors into muscle proteins was studied in isolated rat hemidiaphragms. A mixture of three… (More)
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