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Tyrosine Nitration

Known as: NT, Nitration of Tyrosine 
A biochemical reaction that covalently attaches a nitro group to the carbon at position 3 of the side chain benzene ring of L-tyrosine.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
S-Nitrosylation of Peroxiredoxin II E Promotes Peroxynitrite-Mediated Tyrosine Nitration[W][OA]
Nitric oxide (NO) is a free radical product of cell metabolism that plays diverse and important roles in the regulation of… 
Review
2006
Review
2006
Standardisation of lung function testing: helpful guidance from the ATS/ERS Task Force
A critical overview of the new ATS/ERS guidelines The American Thoracic Society and the European Respiratory Society have… 
Highly Cited
2004
Highly Cited
2004
Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats.
Highly Cited
2002
Highly Cited
2002
Ammonia induces MK‐801‐sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes
Astrocytes play a key role in the pathogenesis of ammonia‐induced neurotoxicity and hepatic encephalopathy. As shown here… 
Highly Cited
1997
Highly Cited
1997
Decreased Zinc Affinity of Amyotrophic Lateral Sclerosis‐Associated Superoxide Dismutase Mutants Leads to Enhanced Catalysis of Tyrosine Nitration by Peroxynitrite
Abstract: Mutations to Cu/Zn superoxide dismutase (SOD) linked to familial amyotrophic lateral sclerosis (ALS) enhance an unknown… 
Highly Cited
1997
Highly Cited
1997
Activation of NF‐κB protects hippocampal neurons against oxidative stress‐induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and…
The transcription factor NF‐κB is expressed in neurons wherein it is activated in response to a variety of stress‐ and injury… 
Highly Cited
1997
Highly Cited
1997
Tyrosine Nitration as a Mechanism of Selective Inactivation of Prostacyclin Synthase by Peroxynitrite
Vascular tone critically depends on the endothelial release of nitric oxide and prostacyclin. Superoxide anions counteract these… 
Highly Cited
1997
Highly Cited
1997
Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols.
Peroxynitrite is a cytotoxic species generated by the reaction between superoxide and nitric oxide. The ability of catechins and… 
Highly Cited
1997
Highly Cited
1997
Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite
Involvement of peroxynitrite (ONOO−) in inflammatory diseases has been implicated by detection of 3-nitrotyrosine, an allegedly… 
Highly Cited
1985
Highly Cited
1985
Reactions of nitrogen dioxide in aqueous model systems: oxidation of tyrosine units in peptides and proteins.
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