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Tumor Suppressor Proteins

Known as: Tumor Suppressor Protein, Proteins, Tumor Suppressor, Tumor Suppressor Proteins [Chemical/Ingredient] 
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell… 
National Institutes of Health

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Narrower (34)

ADAM11 protein, humanBAP1 protein, humanDCC protein, humanDLC-1 (deleted in liver cancer) protein, mouse
APC protein, humanCDKN1C protein, humanCDKN3 protein, humanCyclin-Dependent Kinase Inhibitor 2A, human

Broader (1)

Cell Cycle Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Genome-wide Analysis of P53 under Supplemental Material
Review
2005
Review
2005
Mutant conformation of p 53 translated in vitro or in vivo requires functional HSP
The p53 mutant, 143aa, was translated in vitro in either rabbit reticulocyte lysate (RRL) or wheat germ extract (WGE). In RRL… 
2004
2004
Interactions of protein kinase CK2β subunit within the holoenzyme and with other proteins
Protein kinase CK2 is a ubiquitous, highly conserved protein kinase with a tetrameric α2β2 structure. For the formation of this… 
2001
2001
Sp 1 Plays a Critical Role in the Transcriptional Activation of the Human Cyclin-dependent Kinase Inhibitor p 21 WAF 1 / Cip 1 Gene by the p 53 Tumor Suppressor Protein *
In the present study we present evidence for the critical role of Sp1 in the mechanism of transactivation of the human cell cycle… 
Review
1999
Review
1999
Clinical applications of detecting dysfunctional p53 tumor suppressor protein.
The p53 gene encodes for a protein, p53, which plays a critical role in controlling the cell cycle, in DNA repair and in… 
1999
1999
Transformation-defective polyoma middle T antigen mutants defective in PLCgamma, PI-3, or src kinase activation enhance ERK2 activation and promote retinoic acid-induced, cell differentiation like…
In HL-60 human myeloblastic leukemia cells, retinoic acid is known to cause cFMS, RAF, MEK, and ERK2 dependent myeloid cell… 
Review
1998
Review
1998
[Molecular bases of the programmed cell death process: implications of tumor suppressor protein p53 and other proteins in the control of cell cycle. Mechanisms of apoptotic action. Review].
Abstract Apoptosis is a mechanism of cell death that occurs in normal development and on the regulation of vertebrate tissues and… 
1998
1998
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions.
Programmed cell death (PCD), also known as apoptosis, is a genetically controlled cellular response, manifested in… 
1996
1996
FMS (CSF-1 receptor) prolongs cell cycle and promotes retinoic acid-induced hypophosphorylation of retinoblastoma protein, G1 arrest, and cell differentiation.
The effect of the CSF-1 receptor, cFMS, on the phosphorylation of the retinoblastoma (RB) tumor suppressor protein and on the… 
1995
1995
RB phosphorylation in sodium butyrate‐resistant HL‐60 cells: Cross‐resistance to retinoic acid but not vitamin D3
To examine the potential coupling between inducible cellular changes in RB (retinoblastoma) tumor suppressor protein…