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Tumor Suppressor Proteins

Known as: Tumor Suppressor Protein, Proteins, Tumor Suppressor, Tumor Suppressor Proteins [Chemical/Ingredient] 
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (34)

ADAM11 protein, humanBAP1 protein, humanDCC protein, humanDLC-1 (deleted in liver cancer) protein, mouse
APC protein, humanCDKN1C protein, humanCDKN3 protein, humanCyclin-Dependent Kinase Inhibitor 2A, human

Broader (1)

Cell Cycle Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Structural biology of the tumor suppressor p53.
The tumor suppressor protein p53 induces or represses the expression of a variety of target genes involved in cell cycle control… 
Review
2008
Review
2008
ROS and p53: a versatile partnership.
Review
2007
Review
2007
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
Germ line VHL tumor suppressor gene loss-of-function mutations cause von Hippel-Lindau disease, which is associated with an… 
Highly Cited
2005
Highly Cited
2005
The Menin Tumor Suppressor Protein Is an Essential Oncogenic Cofactor for MLL-Associated Leukemogenesis
Highly Cited
2005
Highly Cited
2005
The Parafibromin Tumor Suppressor Protein Is Part of a Human Paf1 Complex
ABSTRACT Parafibromin, the product of the HRPT2 (hyperparathyroidism-jaw tumor syndrome 2) tumor suppressor gene, is the human… 
Review
2000
Review
2000
MDM2--master regulator of the p53 tumor suppressor protein.
Review
1999
Review
1999
Regulation of the p53 Tumor Suppressor Protein*
Mutations in the p53 tumor suppressor gene occur in about 50% of all human tumors, making it the most frequent target for genetic… 
Highly Cited
1999
Highly Cited
1999
p53 inhibition by the LANA protein of KSHV protects against cell death
Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, has been implicated in the development of Kaposi's… 
Highly Cited
1994
Highly Cited
1994
Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein
ZO-1 is a 210-225-kD peripheral membrane protein associated with cytoplasmic surfaces of the zonula occludens or tight junction… 
Highly Cited
1994
Highly Cited
1994
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
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