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Cyclin-Dependent Kinase Inhibitor 2A, human

Known as: Cell Cycle Negative Regulator Beta, CDKN2A-p16(INK4a), MTS1 
Cyclin-dependent kinase inhibitor 2A (156 aa, ~17 kDa) is encoded by the human CDKN2A gene. This protein is involved in the inhibition of both cell… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
In the last decade, optimized treatment for non-small cell lung cancer had lead to improved prognosis, but the overall survival… Expand
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Highly Cited
2013
Highly Cited
2013
Glioblastoma (GB) is the most common and aggressive primary brain malignancy, with poor prognosis and a lack of effective… Expand
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Highly Cited
2012
Highly Cited
2012
Cancer is a disease driven by genetic variation and mutation. Exome sequencing can be utilized for discovering these variants and… Expand
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Highly Cited
2011
Highly Cited
2011
The mutational profile of head and neck cancer is complex and may pose challenges to the development of targeted therapies. Head… Expand
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Highly Cited
2011
Highly Cited
2011
The mutational profile of head and neck cancer is complex and may pose challenges to the development of targeted therapies. Head… Expand
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Review
2010
Review
2010
Genomic instability is a characteristic of most cancers. In hereditary cancers, genomic instability results from mutations in DNA… Expand
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Highly Cited
2008
Highly Cited
2008
Previously, several individuals with X-linked SCID (SCID-X1) were treated by gene therapy to restore the missing IL-2 receptor… Expand
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Highly Cited
2004
Highly Cited
2004
We conducted a population-based study on glioblastomas in the Canton of Zurich, Switzerland (population, 1.16 million) to… Expand
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Highly Cited
2001
Highly Cited
2001
Cytological screening for cervical cancer or its precursors using Papanicolaou's smear test (Pap test) has been highly efficient… Expand
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Highly Cited
1998
Highly Cited
1998
The two distinct proteins encoded by the CDKN2A locus are specified by translating the common second exon in alternative reading… Expand
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