DCC protein, human

Known as: DCC, Deleted in Colorectal Carcinoma Protein, Netrin Receptor DCC 
Netrin receptor DCC (1447 aa, ~158 kDa) is encoded by the human DCC gene. This protein is involved in both axonal guidance and the regulation of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Extracellular signals regulate protein translation in many cell functions. A key advantage of control at the translational level… (More)
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Highly Cited
2009
Highly Cited
2009
Despite the successes of genomics, little is known about how genetic information produces complex organisms. A look at the… (More)
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Highly Cited
2008
Highly Cited
2008
During nervous system development, spinal commissural axons project toward and across the ventral midline. They are guided in… (More)
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Highly Cited
2004
Highly Cited
2004
Protein kinase A (PKA) exerts a profound influence on axon extension during development and regeneration; however, the molecular… (More)
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Highly Cited
2003
Highly Cited
2003
Netrins promote axon outgrowth and turning through DCC/UNC-40 receptors. To characterize Netrin signaling, we generated a gain-of… (More)
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Highly Cited
2001
Highly Cited
2001
Axonal growth cones that cross the nervous system midline change their responsiveness to midline guidance cues: They become… (More)
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Highly Cited
2001
Highly Cited
2001
The membrane receptors DCC and UNC5H have been shown to be crucial for axon guidance and neuronal migration by acting as… (More)
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Highly Cited
2001
Highly Cited
2001
The expression of DCC (deleted in colorectal cancer) is often markedly reduced in colorectal and other cancers. However, the… (More)
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Highly Cited
1997
Highly Cited
1997
Embryonic retinal ganglion cell (RGC) axons must extend toward and grow through the optic disc to exit the eye into the optic… (More)
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Highly Cited
1996
Highly Cited
1996
UNC-6 netrin, a laminin-related protein secreted from neuroglia and neurons along the ventral midline, orients migrating cells… (More)
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