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DCC protein, human

Known as: DCC, Deleted in Colorectal Carcinoma Protein, Netrin Receptor DCC 
Netrin receptor DCC (1447 aa, ~158 kDa) is encoded by the human DCC gene. This protein is involved in both axonal guidance and the regulation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Extracellular signals regulate protein translation in many cell functions. A key advantage of control at the translational level… Expand
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Highly Cited
2004
Highly Cited
2004
The expression of the protein DCC (deleted in colorectal cancer) is lost or markedly reduced in numerous cancers and in the… Expand
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Highly Cited
2004
Highly Cited
2004
The axon guidance cue netrin is importantly involved in neuronal development. DCC (deleted in colorectal cancer) is a functional… Expand
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Highly Cited
2003
Highly Cited
2003
Signalling by intracellular second messengers such as cyclic nucleotides and Ca2+ is known to regulate attractive and repulsive… Expand
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Highly Cited
2001
Highly Cited
2001
Axonal growth cones that cross the nervous system midline change their responsiveness to midline guidance cues: They become… Expand
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Highly Cited
2001
Highly Cited
2001
The membrane receptors DCC and UNC5H have been shown to be crucial for axon guidance and neuronal migration by acting as… Expand
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Highly Cited
2001
Highly Cited
2001
Netrins are bifunctional guidance molecules, attracting some axons and repelling others. They act through receptors of the DCC… Expand
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Highly Cited
2001
Highly Cited
2001
Netrins stimulate and orient axon growth through a mechanism requiring receptors of the DCC family. It has been unclear, however… Expand
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Highly Cited
1997
Highly Cited
1997
Embryonic retinal ganglion cell (RGC) axons must extend toward and grow through the optic disc to exit the eye into the optic… Expand
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Highly Cited
1996
Highly Cited
1996
UNC-6 netrin, a laminin-related protein secreted from neuroglia and neurons along the ventral midline, orients migrating cells… Expand
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