Tryptophan Oxygenase

Known as: Tryptophan Pyrrolase, 2,3-Dioxygenase, Tryptophan, L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO1) is an important mechanism of peripheral immune tolerance… (More)
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Highly Cited
2009
Highly Cited
2009
Although nutrients, including amino acids and their metabolites such as serotonin (5-HT), are strong modulators of anxiety… (More)
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Highly Cited
2009
Highly Cited
2009
Some of the tryptophan catabolites produced through the kynurenine pathway (KP), and more particularly the excitotoxin quinolinic… (More)
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Review
2008
Review
2008
Despite extensive research, the current theories on serotonergic dysfunctions and cortisol hypersecretion do not provide… (More)
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Highly Cited
2007
Highly Cited
2007
UNLABELLED The differentiation capacity of human embryonic stem cells (hESCs) holds great promise for therapeutic applications… (More)
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Review
2006
Review
2006
The essential amino acid tryptophan is a constituent of proteins and is also a substrate for two important biosynthetic pathways… (More)
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Highly Cited
2002
Highly Cited
2002
Macrophages exposed to macrophage colony-stimulating factor acquire the capacity to suppress T cell proliferation; this effect is… (More)
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Highly Cited
2001
Highly Cited
2001
Elicitors from the plant pathogen Erwinia carotovora trigger coordinate induction of the tryptophan (Trp) biosynthesis pathway… (More)
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Highly Cited
2001
Highly Cited
2001
A mathematical model for regulation of the tryptophan operon is presented. This model takes into account repression, feedback… (More)
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Highly Cited
1986
Highly Cited
1986
Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase was characterized, taking advantage of its induction by… (More)
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