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Tryptophan Oxygenase

Known as: Tryptophan Pyrrolase, 2,3-Dioxygenase, Tryptophan, L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate… 
National Institutes of Health

Related topics

Related topics

17 relations
IDO1 geneIn BloodProcess of secretionTDO2 gene

Narrower (2)

Indoleamine 2,3-Dioxygenase, humanpeptide-tryptophan 2,3-dioxygenase

Broader (2)

Oxygenasespyrrolooxygenases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1993
Review
1993
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).
Accumulation of quinolinic acid and L-kynurenine occurs in the brain and/or blood following immune activation, and may derive… 
Highly Cited
1969
Highly Cited
1969
Induction of hepatic enzyme synthesis in vivo by adenosine 3', 5'-monophosphate.
Highly Cited
1965
Highly Cited
1965
THE ROLES OF SYNTHESIS AND DEGRADATION IN THE CONTROL OF RAT LIVER TRYPTOPHAN PYRROLASE.
Highly Cited
1964
Highly Cited
1964
REGULATORY MECHANISMS GOVERNING SYNTHESIS OF THE ENZYMES FOR TRYPTOPHAN OXIDATION BY PSEUDOMONAS FLUORESCENS.
Summary: Both co-ordinate and sequential inductions govern the synthesis of the enzymes required for the oxidative dissimilation… 
Highly Cited
1964
Highly Cited
1964
MODE OF ACTION OF GLUCOCORTICOIDS. I. STIMULATION OF GLUCONEOGENESIS INDEPENDENT OF SYNTHESIS DE NOVO OF ENZYMES.
The adrenal glucocorticoids regulate carbohydrate formation and protein synthesis (l-6), but the mechanism by which they… 
Highly Cited
1963
Highly Cited
1963
THE COFACTOR-MEDIATED REGULATION OF APOENZYME LEVELS IN ANIMAL TISSUES. I. THE PYRIDOXINE-INDUCED RISE OF RAT LIVER TYROSINE TRANSAMINASE LEVEL IN VIVO.
Highly Cited
1962
Highly Cited
1962
The effect of hydrocortisone on tyrosine-alpha-ketoglutarate transaminase and tryptophan pyrrolase activities in the isolated, perfused rat liver.
Administration of hydrocortisone or cortisone to rats has been shown to produce a marked increase in hepatic tryptophan pyrrolase… 
Highly Cited
1962
Highly Cited
1962
The purification and properties of liver tryptophan pyrrolase.
Highly Cited
1962
Highly Cited
1962
The effect of 5-fluorouracil on the developmental and adaptive formation of tryptophan pyrrolase.
Highly Cited
1961
Highly Cited
1961
The activation and induction of rat liver tryptophan pyrrolase in vivo by its substrate.
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