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Tryptophan Oxygenase

Known as: Tryptophan Pyrrolase, 2,3-Dioxygenase, Tryptophan, L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) 
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate… 
National Institutes of Health

Related topics

Related topics

17 relations
IDO1 geneIn BloodProcess of secretionTDO2 gene

Narrower (2)

Indoleamine 2,3-Dioxygenase, humanpeptide-tryptophan 2,3-dioxygenase

Broader (2)

Oxygenasespyrrolooxygenases

Papers overview

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Highly Cited
1982
Highly Cited
1982
Location of monovalent cation binding sites in the gramicidin channel.
Six syntheses of gramicidin A have been carried out, each with 90% 13 C enrichment of a single carbonyl carbon these being the… 
Highly Cited
1980
Highly Cited
1980
Stereospecificity of hepatic L-tryptophan 2,3-dioxygenase.
Tryptophan 2,3-dioxygenase [L-tryptophan--oxygen 2,3-oxidoreductase (decyclizing), EC 1.13.11.11] has been reported to act solely… 
Review
1967
Review
1967
Enzymatic studies on the hydroxylation of kynurenine in Drosophila melanogaster.
HE classic pathway for brown pigment synthesis in Drosophila melanogaster, as determined by the accumulation of intermediates… 
Highly Cited
1965
Highly Cited
1965
Hydrocortisone stimulation of RNA synthesis in induction of hepatic enzymes.
Increased synthesis of hepatic enzymes due to hydrocortisone is preceded by an increase in the rate of synthesis of nuclear RNA… 
Highly Cited
1964
Highly Cited
1964
REGULATORY MECHANISMS GOVERNING SYNTHESIS OF THE ENZYMES FOR TRYPTOPHAN OXIDATION BY PSEUDOMONAS FLUORESCENS.
Summary: Both co-ordinate and sequential inductions govern the synthesis of the enzymes required for the oxidative dissimilation… 
Highly Cited
1964
Highly Cited
1964
MODE OF ACTION OF GLUCOCORTICOIDS. I. STIMULATION OF GLUCONEOGENESIS INDEPENDENT OF SYNTHESIS DE NOVO OF ENZYMES.
The adrenal glucocorticoids regulate carbohydrate formation and protein synthesis (l-6), but the mechanism by which they… 
Highly Cited
1964
Highly Cited
1964
STUDIES ON THE MECHANISM OF DIETHYLSTILBESTROL-INDUCED FORMATION OF PHOSPHOPROTEIN IN MALE CHICKENS.
The blood of laying contains a phosphoprotein fraction that is absent from the blood of nonlaying cockerels This material, like… 
Highly Cited
1962
Highly Cited
1962
The effect of hydrocortisone on tyrosine-alpha-ketoglutarate transaminase and tryptophan pyrrolase activities in the isolated, perfused rat liver.
Administration of hydrocortisone or cortisone to rats has been shown to produce a marked increase in hepatic tryptophan pyrrolase… 
Highly Cited
1962
Highly Cited
1962
The effect of 5-fluorouracil on the developmental and adaptive formation of tryptophan pyrrolase.
Highly Cited
1961
Highly Cited
1961
Metabolic adaptations in rat hepatomas. II. Tryptophan pyrrolase and tyrosine alpha-ketoglutarate transaminase.
Summary The administration of tryptophan or cortisone to rats bearing the Morris 5123 Hepatoma resulted in significant increases… 
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