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TDO2 gene

Known as: TDO2, TRYPTOPHAN OXYGENASE, TPH2 
This gene plays a role in tryptophan catabolism.
National Institutes of Health

Related topics

Related topics

6 relations
Catabolic ProcessOxidation-ReductionTryptophan OxygenaseTryptophanase

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TDO2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase.
Highly Cited
2012
Highly Cited
2012
Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms.
Highly Cited
2008
Highly Cited
2008
No association between a TPH2 promoter polymorphism and mood disorders or monoamine turnover.
2007
2007
Influence of human tryptophan hydroxylase 2 N‐ and C‐terminus on enzymatic activity and oligomerization
Tryptophan hydroxylase (TPH) catalyses the first and rate limiting step in the biosynthesis of the neurotransmitter serotonin… 
Highly Cited
2001
Highly Cited
2001
Patterns of DNA sequence variation in chromosomally recognized taxa of Anopheles gambiae: evidence from rDNA and single‐copy loci
Patterns of DNA sequence variation in the ribosomal DNA (rDNA) second internal transcribed spacer (ITS2) and five unlinked single… 
1986
1986
Developmental control of gene expression of tryptophan 2,3-dioxygenase in neonatal rat liver.
1986
1986
Regulation of gene expression in rat hepatocytes and hepatoma cells by insulin: quantitation of messenger ribonucleic acid's coding for tyrosine aminotransferase, tryptophan oxygenase, and…
The effect of insulin on the abundance of mRNAs coding for tyrosine aminotransferase (TAT; EC 2.6.1.5), tryptophan oxygenase (TO… 
1983
1983
Hormonal regulation of translatable mRNA of tryptophan 2,3-dioxygenase in primary cultures of adult rat hepatocytes.
Tryptophan 2,3-dioxygenase [EC 1.13.11.11] in primary cultures of adult rat hepatocytes was induced 3-4 fold by 1 microM… 
Highly Cited
1973
Highly Cited
1973
Messenger RNA for hepatic tryptophan oxygenase: its partial purification, its translation in a heterologous cell-free system, and its control by glucocorticoid hormones.
Messenger RNA from rat liver was partially purified by chromatography on cellulose on the basis of its poly(A) content. Microgram… 
Highly Cited
1971
Highly Cited
1971
Effects of sex hormones on three glucocorticoid-inducible enzymes concerned with amino acid metabolism in rat liver.
The activities of three glucocorticoid-inducible enzymes, tryptophan oxygenase, tyrosine aminotransferase and alanine… 
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