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Indoleamine 2,3-Dioxygenase, human

Known as: Indoleamine-Pyrrole 2,3-Dioxygenase, IDO, EC 1.13.11.52 
Indoleamine 2,3-dioxygenase (403 aa, ~45 kDa) is encoded by the human INDO gene. This protein is involved in the degradation of tryptophan.
National Institutes of Health

Papers overview

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2014
2014
Meeting abstracts Clinical Trial Registration Number: [NCT02048709][1] The enzyme Indoleamine 2,3-dioxygenase (IDO1) catalyzes… 
Review
2013
Review
2013
Munn et al. made a scientific observation of major biological importance. For the first time they showed that in the mammal the… 
Review
2010
Review
2010
We describe herein for the first time our medicinal electronomics bricolage design of hypoxia-targeting antineoplastic drugs and… 
Highly Cited
2006
Highly Cited
2006
Indoleamine 2,3-dioxygenase (IDO) is a tryptophan degradation enzyme that is emerging as an important drug target. IDO is… 
Review
2005
Review
2005
Activation of the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) in cancer cells facilitates immune escape. A… 
2003
2003
We have already reported that exercise activates kynurenine pathway. But, the mechanism for this activation by exercise is still… 
2002
2002
The mechanisms by which tumour cells escape recognition by the immune system or subvert antitumour effector responses remain… 
Review
1996
Review
1996
The following is our current working hypothesis concerning the biological significance of IDO induction. When tissues are invaded…