Indoleamine-Pyrrole 2,3,-Dioxygenase

Known as: Indoleamine-Pyrrole 2,3,-Dioxygenase [Chemical/Ingredient], Indolamine 2,3 Dioxygenase, Indolamine-2,3-Dioxygenase 
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The treatment of bladder cancer has evolved over time to encompass not only the traditional modalities of chemotherapy and… (More)
  • figure 1
  • table 1
  • table 1
  • table 1
  • table 2
Is this relevant?
Highly Cited
2013
Highly Cited
2013
The cytotoxic T lymphocyte antigen-4 (CTLA-4)-blocking antibody ipilimumab results in durable responses in metastatic melanoma… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
The pathogenesis of human and simian immunodeficiency viruses is characterized by CD4(+) T cell depletion and chronic T cell… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2007
Review
2007
Tumors arise from normal cells of the body through genetic mutation. Although such genetic mutation often leads to the expression… (More)
  • figure 1
  • figure 2
Is this relevant?
2007
2007
Dendritic cell (DC)-based cancer vaccines are currently being evaluated as novel anti-tumor vaccination strategies, but in some… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Indoleamine 2,3-dioxygenase (IDO) is an immunosuppressive enzyme that contributes to tolerance in a number of biological settings… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Prostaglandins, a family of lipidic molecules released during inflammation, display immunomodulatory properties in several models… (More)
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
One mechanism contributing to immunologic unresponsiveness toward tumors may be presentation of tumor antigens by tolerogenic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Marrow stromal cells (MSCs) inhibit allogeneic T-cell responses, yet the molecular mechanism mediating this immunosuppressive… (More)
  • figure 2
  • figure 1
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Antigen-presenting cells (APCs) can induce tolerance or immunity. We describe a subset of human APCs that express indoleamine 2,3… (More)
Is this relevant?